Abstract
A galactocerebroside (BAC-4-4a) was obtained from its parent galactocerebroside molecular species (BAC-4) by using two types of reversed-phase HPLC column. The parent cerebroside BAC-4 has been isolated from less polar lipid fraction of CHCl3/MeOH extract of sea cucumber Bohadschia argus, together with known typical types of glucocerebroside molecular species. The structure of BAC-4-4a was determined on the basis of chemical and spectroscopic evidences as 1-O-(β-D-galactopyranosyl)-(25,3R, 4,E)-2[(2′R,15′Z)-2-hydroxytetracosenoyl-amino]-4-heptadecene-1, 3-diol. This is the first report of isolation and structure determination of galactocerebro-side from sea cucumber.
Original language | English |
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Pages (from-to) | 315-317 |
Number of pages | 3 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 57 |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 1 2009 |
All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Drug Discovery