Abstract
A galactocerebroside (BAC-4-4a) was obtained from its parent galactocerebroside molecular species (BAC-4) by using two types of reversed-phase HPLC column. The parent cerebroside BAC-4 has been isolated from less polar lipid fraction of CHCl3/MeOH extract of sea cucumber Bohadschia argus, together with known typical types of glucocerebroside molecular species. The structure of BAC-4-4a was determined on the basis of chemical and spectroscopic evidences as 1-O-(β-D-galactopyranosyl)-(25,3R, 4,E)-2[(2′R,15′Z)-2-hydroxytetracosenoyl-amino]-4-heptadecene-1, 3-diol. This is the first report of isolation and structure determination of galactocerebro-side from sea cucumber.
| Original language | English |
|---|---|
| Pages (from-to) | 315-317 |
| Number of pages | 3 |
| Journal | Chemical and Pharmaceutical Bulletin |
| Volume | 57 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - Mar 1 2009 |
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All Science Journal Classification (ASJC) codes
- Chemistry(all)
- Drug Discovery
Cite this
Isolation and structure of a galactocerebroside from the sea cucumber bohadschia argus. / Ikeda, Yuriko; Inagaki, Masanori; Yamada, Koji; Zhang, Xiao Wen; Zhang, Bo; Miyamoto, Tomofumi; Higuchi, Ryuichi.
In: Chemical and Pharmaceutical Bulletin, Vol. 57, No. 3, 01.03.2009, p. 315-317.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Isolation and structure of a galactocerebroside from the sea cucumber bohadschia argus
AU - Ikeda, Yuriko
AU - Inagaki, Masanori
AU - Yamada, Koji
AU - Zhang, Xiao Wen
AU - Zhang, Bo
AU - Miyamoto, Tomofumi
AU - Higuchi, Ryuichi
PY - 2009/3/1
Y1 - 2009/3/1
N2 - A galactocerebroside (BAC-4-4a) was obtained from its parent galactocerebroside molecular species (BAC-4) by using two types of reversed-phase HPLC column. The parent cerebroside BAC-4 has been isolated from less polar lipid fraction of CHCl3/MeOH extract of sea cucumber Bohadschia argus, together with known typical types of glucocerebroside molecular species. The structure of BAC-4-4a was determined on the basis of chemical and spectroscopic evidences as 1-O-(β-D-galactopyranosyl)-(25,3R, 4,E)-2[(2′R,15′Z)-2-hydroxytetracosenoyl-amino]-4-heptadecene-1, 3-diol. This is the first report of isolation and structure determination of galactocerebro-side from sea cucumber.
AB - A galactocerebroside (BAC-4-4a) was obtained from its parent galactocerebroside molecular species (BAC-4) by using two types of reversed-phase HPLC column. The parent cerebroside BAC-4 has been isolated from less polar lipid fraction of CHCl3/MeOH extract of sea cucumber Bohadschia argus, together with known typical types of glucocerebroside molecular species. The structure of BAC-4-4a was determined on the basis of chemical and spectroscopic evidences as 1-O-(β-D-galactopyranosyl)-(25,3R, 4,E)-2[(2′R,15′Z)-2-hydroxytetracosenoyl-amino]-4-heptadecene-1, 3-diol. This is the first report of isolation and structure determination of galactocerebro-side from sea cucumber.
UR - http://www.scopus.com/inward/record.url?scp=62549135688&partnerID=8YFLogxK
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U2 - 10.1248/cpb.57.315
DO - 10.1248/cpb.57.315
M3 - Article
VL - 57
SP - 315
EP - 317
JO - Chemical and Pharmaceutical Bulletin
JF - Chemical and Pharmaceutical Bulletin
SN - 0009-2363
IS - 3
ER -