Isothiouronium-based amphiphilic gold nanoparticles with a colorimetric response to hydrophobic anions in water: a new strategy for fluoride ion detection in the presence of a phenylboronic acid

Tsuyoshi Minami, Kenji Kaneko, Takeshi Nagasaki, Yuji Kubo

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Gold nanoparticles modified with isothiouronium-derived amphiphile units 1 were prepared by the reduction of AuCl4- (n - C8 H17)4 N+ with NaBH4 in the presence of bis(5-(N-(2-(2-methoxyethoxy)ethyl)-N-methyl-S-isothiouronio)pentyl) disulfide 2. The obtained nanoparticles 1 showed a selective coloration for hydrophobic anions in water, possibly due to an anion exchange and subsequent aggregation. On the basis of this observation, the detection of F- in water has been achieved using 3-nitrophenylboronic acid as a mediator at pH 5.5, thereby providing a new strategy for the design of a F- sensory system.

Original languageEnglish
Pages (from-to)432-436
Number of pages5
JournalTetrahedron Letters
Volume49
Issue number3
DOIs
Publication statusPublished - Jan 14 2008

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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