Itch in Atopic Dermatitis

Makiko Kido-Nakahara, Masutaka Furue, Dugarmaa Ulzii, Takeshi Nakahara

Research output: Contribution to journalReview articlepeer-review

31 Citations (Scopus)

Abstract

Chronic itch in inflammatory skin diseases, such as atopic dermatitis, markedly diminishes the quality of life of affected individuals. Comprehensive progress has been made in understanding itch signaling and associated mediators in the skin, dorsal root ganglia, spinal cord, and central nervous system, which may amplify or suppress atopic itch. Conventional therapies for atopic dermatitis are capable of reducing atopic itch; however, most patients are not satisfied with the antipruritic capacity of conventional treatments. Exploring itch pathways and mechanisms may lead to novel therapeutic approaches for atopic itch.

Original languageEnglish
Pages (from-to)113-122
Number of pages10
JournalImmunology and Allergy Clinics of North America
Volume37
Issue number1
DOIs
Publication statusPublished - Feb 1 2017

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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