Knowledge-based system for computer-aided drug design

E. Suzuki, T. Akutsu, S. Ohsuga

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

The paper presents dd-chaus, a drug design aiding system based on a logic-programming approach. One of its characteristics is that it addresses the combinatorial-explosion problem. This has been realized in two ways: representing design strategies as meta rules (dp_meta), and simulating the design examples of the past according to the analogy between chemical graphs (dp_analogy). A special format to describe knowledge of drug design, emil data sheet, is used to acquire expert knowledge. Compared with other drug design aiding systems, dd-chaus is more flexible in terms of the description, management and utilization of knowledge and strategies.

Original languageEnglish
Pages (from-to)114-126
Number of pages13
JournalKnowledge-Based Systems
Volume6
Issue number2
DOIs
Publication statusPublished - Jun 1993
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Management Information Systems
  • Software
  • Information Systems and Management
  • Artificial Intelligence

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