Label-free detection of antigen protein using a metal mesh device surface-modified by an antibody

Hirokazu Seto, Seiji Kamba, Takashi Kondo, Yuichi Ogawa, Yu Hoshino, Yoshiko Miura

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A biosensor for protein detection was developed using antibody-immobilized metal mesh devices. Antihemoglobin antibodies were covalently immobilized on a metal mesh device. Extraordinary transmission with a dipped structure was observed for a metal mesh device immobilized with antihemoglobin antibodies as well as for the original metal mesh device. Hemoglobin in the mixture solution containing albumin at a hundred-fold concentration was detectable using antihemoglobin-immobilized MMDs. The detectability using the antihemoglobin-immobilized metal mesh device was similar to that of a commercially-available kit for the qualitative determination of hemoglobin.

Original languageEnglish
Pages (from-to)173-176
Number of pages4
Journalanalytical sciences
Volume31
Issue number3
DOIs
Publication statusPublished - 2015

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry

Fingerprint Dive into the research topics of 'Label-free detection of antigen protein using a metal mesh device surface-modified by an antibody'. Together they form a unique fingerprint.

Cite this