Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria: Overview and limits

Mohamed Ali Sayed Mohamed Abdelrahman, Yukihiro Tashiro, Kenji Sonomoto

Research output: Contribution to journalReview article

238 Citations (Scopus)

Abstract

Lactic acid is an industrially important product with a large and rapidly expanding market due to its attractive and valuable multi-function properties. The economics of lactic acid production by fermentation is dependent on many factors, of which the cost of the raw materials is very significant. It is very expensive when sugars, e.g., glucose, sucrose, starch, etc., are used as the feedstock for lactic acid production. Therefore, lignocellulosic biomass is a promising feedstock for lactic acid production considering its great availability, sustainability, and low cost compared to refined sugars. Despite these advantages, the commercial use of lignocellulose for lactic acid production is still problematic. This review describes the " conventional" processes for producing lactic acid from lignocellulosic materials with lactic acid bacteria. These processes include: pretreatment of the biomass, enzyme hydrolysis to obtain fermentable sugars, fermentation technologies, and separation and purification of lactic acid. In addition, the difficulties associated with using this biomass for lactic acid production are especially introduced and several key properties that should be targeted for low-cost and advanced fermentation processes are pointed out. We also discuss the metabolism of lignocellulose-derived sugars by lactic acid bacteria.

Original languageEnglish
Pages (from-to)286-301
Number of pages16
JournalJournal of Biotechnology
Volume156
Issue number4
DOIs
Publication statusPublished - Dec 20 2011

Fingerprint

Lactic acid
Sugars
Lactic Acid
Bacteria
Biomass
Fermentation
Sugar (sucrose)
Costs and Cost Analysis
Feedstocks
lignocellulose
Costs
Sugar Acids
Starch
Metabolism
Purification
Glucose
Sucrose
Sustainable development
Hydrolysis
Raw materials

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology

Cite this

Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria : Overview and limits. / Abdelrahman, Mohamed Ali Sayed Mohamed; Tashiro, Yukihiro; Sonomoto, Kenji.

In: Journal of Biotechnology, Vol. 156, No. 4, 20.12.2011, p. 286-301.

Research output: Contribution to journalReview article

Abdelrahman, Mohamed Ali Sayed Mohamed ; Tashiro, Yukihiro ; Sonomoto, Kenji. / Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria : Overview and limits. In: Journal of Biotechnology. 2011 ; Vol. 156, No. 4. pp. 286-301.
@article{f6158b830e464d829baa0fdbbf8c0012,
title = "Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria: Overview and limits",
abstract = "Lactic acid is an industrially important product with a large and rapidly expanding market due to its attractive and valuable multi-function properties. The economics of lactic acid production by fermentation is dependent on many factors, of which the cost of the raw materials is very significant. It is very expensive when sugars, e.g., glucose, sucrose, starch, etc., are used as the feedstock for lactic acid production. Therefore, lignocellulosic biomass is a promising feedstock for lactic acid production considering its great availability, sustainability, and low cost compared to refined sugars. Despite these advantages, the commercial use of lignocellulose for lactic acid production is still problematic. This review describes the {"} conventional{"} processes for producing lactic acid from lignocellulosic materials with lactic acid bacteria. These processes include: pretreatment of the biomass, enzyme hydrolysis to obtain fermentable sugars, fermentation technologies, and separation and purification of lactic acid. In addition, the difficulties associated with using this biomass for lactic acid production are especially introduced and several key properties that should be targeted for low-cost and advanced fermentation processes are pointed out. We also discuss the metabolism of lignocellulose-derived sugars by lactic acid bacteria.",
author = "Abdelrahman, {Mohamed Ali Sayed Mohamed} and Yukihiro Tashiro and Kenji Sonomoto",
year = "2011",
month = "12",
day = "20",
doi = "10.1016/j.jbiotec.2011.06.017",
language = "English",
volume = "156",
pages = "286--301",
journal = "Journal of Biotechnology",
issn = "0168-1656",
publisher = "Elsevier",
number = "4",

}

TY - JOUR

T1 - Lactic acid production from lignocellulose-derived sugars using lactic acid bacteria

T2 - Overview and limits

AU - Abdelrahman, Mohamed Ali Sayed Mohamed

AU - Tashiro, Yukihiro

AU - Sonomoto, Kenji

PY - 2011/12/20

Y1 - 2011/12/20

N2 - Lactic acid is an industrially important product with a large and rapidly expanding market due to its attractive and valuable multi-function properties. The economics of lactic acid production by fermentation is dependent on many factors, of which the cost of the raw materials is very significant. It is very expensive when sugars, e.g., glucose, sucrose, starch, etc., are used as the feedstock for lactic acid production. Therefore, lignocellulosic biomass is a promising feedstock for lactic acid production considering its great availability, sustainability, and low cost compared to refined sugars. Despite these advantages, the commercial use of lignocellulose for lactic acid production is still problematic. This review describes the " conventional" processes for producing lactic acid from lignocellulosic materials with lactic acid bacteria. These processes include: pretreatment of the biomass, enzyme hydrolysis to obtain fermentable sugars, fermentation technologies, and separation and purification of lactic acid. In addition, the difficulties associated with using this biomass for lactic acid production are especially introduced and several key properties that should be targeted for low-cost and advanced fermentation processes are pointed out. We also discuss the metabolism of lignocellulose-derived sugars by lactic acid bacteria.

AB - Lactic acid is an industrially important product with a large and rapidly expanding market due to its attractive and valuable multi-function properties. The economics of lactic acid production by fermentation is dependent on many factors, of which the cost of the raw materials is very significant. It is very expensive when sugars, e.g., glucose, sucrose, starch, etc., are used as the feedstock for lactic acid production. Therefore, lignocellulosic biomass is a promising feedstock for lactic acid production considering its great availability, sustainability, and low cost compared to refined sugars. Despite these advantages, the commercial use of lignocellulose for lactic acid production is still problematic. This review describes the " conventional" processes for producing lactic acid from lignocellulosic materials with lactic acid bacteria. These processes include: pretreatment of the biomass, enzyme hydrolysis to obtain fermentable sugars, fermentation technologies, and separation and purification of lactic acid. In addition, the difficulties associated with using this biomass for lactic acid production are especially introduced and several key properties that should be targeted for low-cost and advanced fermentation processes are pointed out. We also discuss the metabolism of lignocellulose-derived sugars by lactic acid bacteria.

UR - http://www.scopus.com/inward/record.url?scp=82955162743&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=82955162743&partnerID=8YFLogxK

U2 - 10.1016/j.jbiotec.2011.06.017

DO - 10.1016/j.jbiotec.2011.06.017

M3 - Review article

C2 - 21729724

AN - SCOPUS:82955162743

VL - 156

SP - 286

EP - 301

JO - Journal of Biotechnology

JF - Journal of Biotechnology

SN - 0168-1656

IS - 4

ER -