Lacticin Q, a lactococcal bacteriocin, causes high-level membrane permeability in the absence of specific receptors

Fuminori Yoneyama, Yuichi Imura, Shiro Ichimasa, Koji Fujita, Takeshi Zendo, Jiro Nakayama, Katsumi Matsuzaki, Kenji Sonomoto

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

To characterize the mode of action of lacticin Q (LnqQ), its membrane-permeabilizing activity was compared with that of nisin A because of the similar antimicrobial features of these compounds. Lipid II, the receptor for nisin A, was not required for LnqQ activity. LnqQ induced high-level membrane permeability in the absence of specific receptors.

Original languageEnglish
Pages (from-to)538-541
Number of pages4
JournalApplied and environmental microbiology
Volume75
Issue number2
DOIs
Publication statusPublished - Jan 1 2009

Fingerprint

Bacteriocins
nisin
membrane permeability
bacteriocins
Permeability
permeability
membrane
receptors
Membranes
mechanism of action
anti-infective agents
lipid
lipids
nisin A
muramyl-NAc-(pentapeptide)pyrophosphoryl-undecaprenol

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

Cite this

Lacticin Q, a lactococcal bacteriocin, causes high-level membrane permeability in the absence of specific receptors. / Yoneyama, Fuminori; Imura, Yuichi; Ichimasa, Shiro; Fujita, Koji; Zendo, Takeshi; Nakayama, Jiro; Matsuzaki, Katsumi; Sonomoto, Kenji.

In: Applied and environmental microbiology, Vol. 75, No. 2, 01.01.2009, p. 538-541.

Research output: Contribution to journalArticle

Yoneyama, Fuminori ; Imura, Yuichi ; Ichimasa, Shiro ; Fujita, Koji ; Zendo, Takeshi ; Nakayama, Jiro ; Matsuzaki, Katsumi ; Sonomoto, Kenji. / Lacticin Q, a lactococcal bacteriocin, causes high-level membrane permeability in the absence of specific receptors. In: Applied and environmental microbiology. 2009 ; Vol. 75, No. 2. pp. 538-541.
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