Lactols in stereoselection 3. Highly anti-cram selective 1,2-asymmetric induction

Katsuhiko Tomooka, Tatsuyuki Okinaga, Keisuke Suzuki, Gen ichi Tsuchihashi

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)


Nucleophilic addition of MeTi(O-iPr)3 to α-chiral lactols proceeds in highly diastereoselective manner. The sense of the diastereofacial selection is anti-Cram-type, which provides a new and useful method for 1,2-asymmetric induction.

Original languageEnglish
Pages (from-to)1563-1566
Number of pages4
JournalTetrahedron Letters
Issue number12
Publication statusPublished - 1989
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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