Nucleophilic addition of MeTi(O-iPr)3 to α-chiral lactols proceeds in highly diastereoselective manner. The sense of the diastereofacial selection is anti-Cram-type, which provides a new and useful method for 1,2-asymmetric induction.
|Number of pages||4|
|Publication status||Published - 1989|
All Science Journal Classification (ASJC) codes
- Drug Discovery
- Organic Chemistry