Laparoscopic splenectomy for hematologic diseases

Kazuo Tanoue, Keishi Okita, Tomohiko Akahoshi, Kouzou Konishi, Norikazu Gotoh, Norifumi Tsutsumi, Morimasa Tomikawa, Makoto Hashizume

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

Background. Laparoscopic splenectomy has been demonstrated to be technically feasible and safe for the treatment of hematologic diseases. Methods. The study comprised 64 consecutive patients with chronic immune thrombocytopenia purpura (ITP) who were admitted to our hospital from 1992 to 2000 and underwent laparoscopic splenectomy. Forty-one consecutive patients with ITP who underwent open splenectomy performed at the same hospital by the same surgical team between 1986 and 2000 were selected as the control group. Results. We performed laparoscopic splenectomies for ITP, hereditary spherocytosis (HS), malignant lymphoma, autoimmune hemolytic anemia, and cryoglobulinemia. Laparoscopic surgery as compared with open surgery in ITP revealed a significantly lower pain medication requirement, an earlier resumption of oral intake, and a shorter hospital stay, but a longer operative time. During the present study (range: 3.8-80 months), the cumulative rate of nonrecurrence was 67.9% at 5years after surgery, which was similar to the rate for the previous open splenectomy. Conclusions. Laparoscopic splenectomy is considered to be a suitable alternative therapeutic modality in the treatment of hematologic diseases.

Original languageEnglish
Pages (from-to)S318-S323
JournalSurgery
Volume131
Issue number1 SUPPL.
DOIs
Publication statusPublished - 2002

All Science Journal Classification (ASJC) codes

  • Surgery

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