Abstract
Fifty-seven patients with hypopharyngeal cancer treated by irradiation at Kyushu University Hospital between 1985 and 1992 were analyzed retrospectively. They included 53 men and 4 women, and their ages ranged from 39 to 83 years (mean, 63 years). Two patients had stage I, 7 had stage II, 13 had stage III, and 35 had stage IV disease according to the UICC (1997) classification. Initially, they were irradiated in the conventional way with a dose of 30 Gy, and 17 patients with good response were irradiated to curative dose (more than 60 Gy), and 32 patients with poor response were operated immediately. Medically inoperable or unresectable patients were treated in a semiradical way (n=8). The 5-year overall and cause-specific survival rates were 46 % and 51 %, respectively. Five-year cause-specific survival rates were 88 % for stages I and II (n=9), 67 % for stage III (n=13), and 35 % for stage IV (n=35). Five-year cause-specific survival according to treatment method was 58 % for surgery and 51 % for curative radiotherapy. There was no statistically significant difference between the two rates. These results suggest that initial radiation response is an important factor in deciding on the following treatment method. Curative radiotherapy for hypopharyngeal cancer according to initial radiation response is a desirable treatment strategy.
| Original language | English |
|---|---|
| Pages (from-to) | 570-573 |
| Number of pages | 4 |
| Journal | Nippon Acta Radiologica |
| Volume | 63 |
| Issue number | 9 |
| Publication status | Published - Nov 25 2003 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
- Oncology
Cite this
Laryngeal preservation with difinitive radiotherapy in radiosensitive hypopharyngeal cancer. / Naonobu, Kunitake; Katsumasa, Nakamura; Yoshiyuki, Shioyama; Yuichiro, Kuratomi; Tomoya, Yamamoto; Hiromi, Terashima; Hiroshi, Honda.
In: Nippon Acta Radiologica, Vol. 63, No. 9, 25.11.2003, p. 570-573.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Laryngeal preservation with difinitive radiotherapy in radiosensitive hypopharyngeal cancer
AU - Naonobu, Kunitake
AU - Katsumasa, Nakamura
AU - Yoshiyuki, Shioyama
AU - Yuichiro, Kuratomi
AU - Tomoya, Yamamoto
AU - Hiromi, Terashima
AU - Hiroshi, Honda
PY - 2003/11/25
Y1 - 2003/11/25
N2 - Fifty-seven patients with hypopharyngeal cancer treated by irradiation at Kyushu University Hospital between 1985 and 1992 were analyzed retrospectively. They included 53 men and 4 women, and their ages ranged from 39 to 83 years (mean, 63 years). Two patients had stage I, 7 had stage II, 13 had stage III, and 35 had stage IV disease according to the UICC (1997) classification. Initially, they were irradiated in the conventional way with a dose of 30 Gy, and 17 patients with good response were irradiated to curative dose (more than 60 Gy), and 32 patients with poor response were operated immediately. Medically inoperable or unresectable patients were treated in a semiradical way (n=8). The 5-year overall and cause-specific survival rates were 46 % and 51 %, respectively. Five-year cause-specific survival rates were 88 % for stages I and II (n=9), 67 % for stage III (n=13), and 35 % for stage IV (n=35). Five-year cause-specific survival according to treatment method was 58 % for surgery and 51 % for curative radiotherapy. There was no statistically significant difference between the two rates. These results suggest that initial radiation response is an important factor in deciding on the following treatment method. Curative radiotherapy for hypopharyngeal cancer according to initial radiation response is a desirable treatment strategy.
AB - Fifty-seven patients with hypopharyngeal cancer treated by irradiation at Kyushu University Hospital between 1985 and 1992 were analyzed retrospectively. They included 53 men and 4 women, and their ages ranged from 39 to 83 years (mean, 63 years). Two patients had stage I, 7 had stage II, 13 had stage III, and 35 had stage IV disease according to the UICC (1997) classification. Initially, they were irradiated in the conventional way with a dose of 30 Gy, and 17 patients with good response were irradiated to curative dose (more than 60 Gy), and 32 patients with poor response were operated immediately. Medically inoperable or unresectable patients were treated in a semiradical way (n=8). The 5-year overall and cause-specific survival rates were 46 % and 51 %, respectively. Five-year cause-specific survival rates were 88 % for stages I and II (n=9), 67 % for stage III (n=13), and 35 % for stage IV (n=35). Five-year cause-specific survival according to treatment method was 58 % for surgery and 51 % for curative radiotherapy. There was no statistically significant difference between the two rates. These results suggest that initial radiation response is an important factor in deciding on the following treatment method. Curative radiotherapy for hypopharyngeal cancer according to initial radiation response is a desirable treatment strategy.
UR - http://www.scopus.com/inward/record.url?scp=1542442437&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=1542442437&partnerID=8YFLogxK
M3 - Article
C2 - 14699866
AN - SCOPUS:1542442437
VL - 63
SP - 570
EP - 573
JO - Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
JF - Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica
SN - 0048-0428
IS - 9
ER -