Lesch-Nyhan syndrome: Successful prevention of lower lip ulceration caused by self-mutilation by use of mouth guard

Toshio Sugahara, Katsuaki Mishima, Yoshihide Mori

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Lesch-Nyhan syndrome (LNS) is a disorder caused by congenital absence of a purine metabolic enzyme, hypoxanthine guanine phosphoribosyltransferase (HGPRT). This syndrome is characterized clinically by hyperuricemia and neurologic features including choreoathetoid spasticity, self-mutilation, and mental retardation. We report on a patient in whom self-mutilation of the lower lip was suppressed with the help of a mouth guard made from soft resin.

Original languageEnglish
Pages (from-to)37-38
Number of pages2
JournalInternational Journal of Oral and Maxillofacial Surgery
Volume23
Issue number1
DOIs
Publication statusPublished - Jan 1 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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