TY - JOUR
T1 - Lesch-Nyhan syndrome
T2 - Successful prevention of lower lip ulceration caused by self-mutilation by use of mouth guard
AU - Sugahara, Toshio
AU - Mishima, Katsuaki
AU - Mori, Yoshihide
PY - 1994/1/1
Y1 - 1994/1/1
N2 - Lesch-Nyhan syndrome (LNS) is a disorder caused by congenital absence of a purine metabolic enzyme, hypoxanthine guanine phosphoribosyltransferase (HGPRT). This syndrome is characterized clinically by hyperuricemia and neurologic features including choreoathetoid spasticity, self-mutilation, and mental retardation. We report on a patient in whom self-mutilation of the lower lip was suppressed with the help of a mouth guard made from soft resin.
AB - Lesch-Nyhan syndrome (LNS) is a disorder caused by congenital absence of a purine metabolic enzyme, hypoxanthine guanine phosphoribosyltransferase (HGPRT). This syndrome is characterized clinically by hyperuricemia and neurologic features including choreoathetoid spasticity, self-mutilation, and mental retardation. We report on a patient in whom self-mutilation of the lower lip was suppressed with the help of a mouth guard made from soft resin.
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U2 - 10.1016/S0901-5027(05)80324-8
DO - 10.1016/S0901-5027(05)80324-8
M3 - Article
C2 - 8163858
AN - SCOPUS:0028380989
VL - 23
SP - 37
EP - 38
JO - International Journal of Oral and Maxillofacial Surgery
JF - International Journal of Oral and Maxillofacial Surgery
SN - 0901-5027
IS - 1
ER -