Lifestyle factors, radiation and gastric cancer in atomic-bomb survivors (Japan)

Catherine Sauvaget, Frédéric Lagarde, Jun Nagano, Midori Soda, Kojiro Koyama, Kazunori Kodama

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Objective: To examine the association between the incidence of gastric cancer and lifestyle factors such as cigarette smoking, alcohol drinking, and diet as well as atomic bomb radiation exposure. Methods: Longitudinal study including 38,576 atomic-bomb survivors in Hiroshima and Nagasaki, Japan, followed-up between 1980 and 1999. Individual radiation dose was estimated according to the Dosimetry System 1986 (DS86). Lifestyle determinants were based on the responses to a mail survey sent at baseline. 1270 incident carcinomas of gastric cancer were identified during the 485,575 person-years of follow-up. Poisson regression was used to estimate incidence rate ratios. Results: Ionizing radiation exposure, male gender, age, and smoking were significantly associated with an increased risk of stomach cancer. No association was suggested between the frequency of consumption of fruit, vegetables, green tea, and soy products and gastric cancer. Conclusions: In this Japanese population, although radiation and smoking were strong determinants of stomach cancer, no supportive evidence could be shown for the effect of dietary factors.

Original languageEnglish
Pages (from-to)773-780
Number of pages8
JournalCancer Causes and Control
Volume16
Issue number7
DOIs
Publication statusPublished - Sep 1 2005

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Nuclear Weapons
Stomach Neoplasms
Survivors
Life Style
Japan
Radiation
Smoking
Incidence
Postal Service
Tea
Ionizing Radiation
Alcohol Drinking
Vegetables
Longitudinal Studies
Fruit
Diet
Carcinoma
Population

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Lifestyle factors, radiation and gastric cancer in atomic-bomb survivors (Japan). / Sauvaget, Catherine; Lagarde, Frédéric; Nagano, Jun; Soda, Midori; Koyama, Kojiro; Kodama, Kazunori.

In: Cancer Causes and Control, Vol. 16, No. 7, 01.09.2005, p. 773-780.

Research output: Contribution to journalArticle

Sauvaget, Catherine ; Lagarde, Frédéric ; Nagano, Jun ; Soda, Midori ; Koyama, Kojiro ; Kodama, Kazunori. / Lifestyle factors, radiation and gastric cancer in atomic-bomb survivors (Japan). In: Cancer Causes and Control. 2005 ; Vol. 16, No. 7. pp. 773-780.
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