TY - JOUR
T1 - Lifestyle factors, radiation and gastric cancer in atomic-bomb survivors (Japan)
AU - Sauvaget, Catherine
AU - Lagarde, Frédéric
AU - Nagano, Jun
AU - Soda, Midori
AU - Koyama, Kojiro
AU - Kodama, Kazunori
N1 - Funding Information:
Permission for use of incidence data was obtained from the Hiroshima and Nagasaki cancer registries. The Radiation Effects Research Foundation (RERF), Hiroshima and Nagasaki, Japan is a private, non-profit foundation funded by the Japanese Ministry of Health, Labour and Welfare (MHLW) and the U.S. Department of Energy (DOE) the latter through the National Academy of Sciences. This publication was supported by RERF Research Protocols RP # 18–61 and 14–78.
PY - 2005/9
Y1 - 2005/9
N2 - Objective: To examine the association between the incidence of gastric cancer and lifestyle factors such as cigarette smoking, alcohol drinking, and diet as well as atomic bomb radiation exposure. Methods: Longitudinal study including 38,576 atomic-bomb survivors in Hiroshima and Nagasaki, Japan, followed-up between 1980 and 1999. Individual radiation dose was estimated according to the Dosimetry System 1986 (DS86). Lifestyle determinants were based on the responses to a mail survey sent at baseline. 1270 incident carcinomas of gastric cancer were identified during the 485,575 person-years of follow-up. Poisson regression was used to estimate incidence rate ratios. Results: Ionizing radiation exposure, male gender, age, and smoking were significantly associated with an increased risk of stomach cancer. No association was suggested between the frequency of consumption of fruit, vegetables, green tea, and soy products and gastric cancer. Conclusions: In this Japanese population, although radiation and smoking were strong determinants of stomach cancer, no supportive evidence could be shown for the effect of dietary factors.
AB - Objective: To examine the association between the incidence of gastric cancer and lifestyle factors such as cigarette smoking, alcohol drinking, and diet as well as atomic bomb radiation exposure. Methods: Longitudinal study including 38,576 atomic-bomb survivors in Hiroshima and Nagasaki, Japan, followed-up between 1980 and 1999. Individual radiation dose was estimated according to the Dosimetry System 1986 (DS86). Lifestyle determinants were based on the responses to a mail survey sent at baseline. 1270 incident carcinomas of gastric cancer were identified during the 485,575 person-years of follow-up. Poisson regression was used to estimate incidence rate ratios. Results: Ionizing radiation exposure, male gender, age, and smoking were significantly associated with an increased risk of stomach cancer. No association was suggested between the frequency of consumption of fruit, vegetables, green tea, and soy products and gastric cancer. Conclusions: In this Japanese population, although radiation and smoking were strong determinants of stomach cancer, no supportive evidence could be shown for the effect of dietary factors.
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U2 - 10.1007/s10552-005-5385-x
DO - 10.1007/s10552-005-5385-x
M3 - Article
C2 - 16132787
AN - SCOPUS:23844437983
SN - 0957-5243
VL - 16
SP - 773
EP - 780
JO - Cancer Causes and Control
JF - Cancer Causes and Control
IS - 7
ER -
