Lifestyle-related diseases and an inter-organ metabolic network

Yasutaka Miyachi, Kyoichiro Tsuchiya, Yoshihiro Ogawa

Research output: Contribution to journalReview article

Abstract

Lifestyle-related diseases such as type 2 diabetes, hypertension and dyslipidemia are a prominent cause of mortality in Japan, and there is a strong requirement for elucidation of detailed molecular mechanisms and effective therapeutic strategies. Obesity-induced adipose tissue inflammation leads to dysregulation of adipokine production, which can cause lifestyle-related diseases. The interaction of organ systems via endocrine or neural networks is recognized as an important factor in the pathogenesis and promotion of lifestyle-related diseases. Therefore, further investigation for the interaction between adipose tissues and bones can provide new treatment strategies of metabolic bone disorders.

Original languageEnglish
Pages (from-to)392-398
Number of pages7
JournalClinical calcium
Volume26
Issue number3
Publication statusPublished - Mar 1 2016
Externally publishedYes

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Metabolic Networks and Pathways
Life Style
Adipose Tissue
Bone and Bones
Endocrine System
Adipokines
Dyslipidemias
Type 2 Diabetes Mellitus
Japan
Obesity
Hypertension
Inflammation
Mortality
Therapeutics

All Science Journal Classification (ASJC) codes

  • Medicine(all)

Cite this

Lifestyle-related diseases and an inter-organ metabolic network. / Miyachi, Yasutaka; Tsuchiya, Kyoichiro; Ogawa, Yoshihiro.

In: Clinical calcium, Vol. 26, No. 3, 01.03.2016, p. 392-398.

Research output: Contribution to journalReview article

Miyachi, Y, Tsuchiya, K & Ogawa, Y 2016, 'Lifestyle-related diseases and an inter-organ metabolic network', Clinical calcium, vol. 26, no. 3, pp. 392-398.
Miyachi, Yasutaka ; Tsuchiya, Kyoichiro ; Ogawa, Yoshihiro. / Lifestyle-related diseases and an inter-organ metabolic network. In: Clinical calcium. 2016 ; Vol. 26, No. 3. pp. 392-398.
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