Light-mediated oxidation of alcohols and mandelate by flavin-metal complexes

Seiji Shinkai, Hideki Nakao, Kaori Ueda, Osamu Manabe

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

New flavins with metal affinity, (1) and (2) were applied to photo-oxidation of alcohols and mandelate. (1) rapidly photo-oxidized alcohols in the presence of Mg(II) and Zn(II): the rate augmentation corresponds to 16-18 fold. (2) could photo-oxidize PhCH(OH)COO-K+ but only slightly PhCH(OH)COO-NMe4 +: the rate difference amounts to 110-fold. Thus, the photo-oxidizability of these modified flavins can be markedly improved through complexation with metal ions.

Original languageEnglish
Pages (from-to)5295-5298
Number of pages4
JournalTetrahedron Letters
Volume25
Issue number46
DOIs
Publication statusPublished - Jan 1 1984
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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