Linear and nonlinear laser-trapping microrheology

C. F. Schmidt; D. Mizuno

doi:10.1117/12.739441

Linear and nonlinear laser-trapping microrheology

C. F. Schmidt, D. Mizuno

Condensed Matter Physics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We have developed a high-bandwidth technique for active 2-particle microrheology (AMR) with which we can probe linear and nonlinear responses of soft materials. Micron-sized colloidal probe particles are driven by an oscillating optical trap, and the resulting correlated motions of neighboring particles are detected by laser interferometry. Lock-in detection at the driving frequency and at its second harmonic makes it possible to measure the linear and the non-linear response of the embedding medium at the same time. We demonstrate the sensitivity of the method by detecting a second-harmonic response in water which is of purely geometric origin and which can be fully understood within linear hydrodynamics.

Original language	English
Title of host publication	Optical Trapping and Optical Micromanipulation IV
DOIs	https://doi.org/10.1117/12.739441
Publication status	Published - Dec 1 2007
Event	Optical Trapping and Optical Micromanipulation IV - San Diego, CA, United States Duration: Aug 26 2007 → Aug 29 2007

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	6644
ISSN (Print)	0277-786X

Other

Other	Optical Trapping and Optical Micromanipulation IV
Country	United States
City	San Diego, CA
Period	8/26/07 → 8/29/07

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Access to Document

10.1117/12.739441

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Schmidt, C. F., & Mizuno, D. (2007). Linear and nonlinear laser-trapping microrheology. In Optical Trapping and Optical Micromanipulation IV [66440L] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6644). https://doi.org/10.1117/12.739441

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abstract = "We have developed a high-bandwidth technique for active 2-particle microrheology (AMR) with which we can probe linear and nonlinear responses of soft materials. Micron-sized colloidal probe particles are driven by an oscillating optical trap, and the resulting correlated motions of neighboring particles are detected by laser interferometry. Lock-in detection at the driving frequency and at its second harmonic makes it possible to measure the linear and the non-linear response of the embedding medium at the same time. We demonstrate the sensitivity of the method by detecting a second-harmonic response in water which is of purely geometric origin and which can be fully understood within linear hydrodynamics.",

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AU - Mizuno, D.

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AB - We have developed a high-bandwidth technique for active 2-particle microrheology (AMR) with which we can probe linear and nonlinear responses of soft materials. Micron-sized colloidal probe particles are driven by an oscillating optical trap, and the resulting correlated motions of neighboring particles are detected by laser interferometry. Lock-in detection at the driving frequency and at its second harmonic makes it possible to measure the linear and the non-linear response of the embedding medium at the same time. We demonstrate the sensitivity of the method by detecting a second-harmonic response in water which is of purely geometric origin and which can be fully understood within linear hydrodynamics.

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