Lipoprotein metabolism, insulin resistance, and adipocytokine levels in Japanese female adolescents with a normal body mass index and high body fat mass

Noriaki Kishimoto, Koichi Okita, Shingo Takada, Ichiro Sakuma, Yasuaki Saijo, Hitoshi Chiba, Kojiro Ishii, Reiko Kishi, Hiroyuki Tsutsui

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: The prevalence of obesity is gradually increasing in Japan, but in women aged in their 20 s to 50 s it has been disproportionately decreasing. However, the exact body composition of this subset of the population has not been elucidated. Methods and Results: Body composition was determined using whole-body dual energy X-ray absorptiometry and metabolic parameters in 157 Japanese female university students (21.1±1.9 years); 31 women had a normal body mass index (BMI), but an increased body fat mass (BFM). Only the 31 had signifcantly higher low-density lipoprotein-cholesterol levels (90.5 vs 99.0 mg/dl, P<0.01) and leptin concentration (7.0 vs 4.6 ng/ml, P<0.05) and lower high-density lipoprotein-cholesterol (80.4±15.1 vs 73.5±14.5 mg/dl, P<0.01) than females with normal BMI and normal BFM. Conclusions: A considerable number of young Japanese women with a normal BMI have excess BFM and relatively higher lipid and leptin levels. These fndings may provide an important basis for future epidemiological surveys and studies.

Original languageEnglish
Pages (from-to)534-539
Number of pages6
JournalCirculation Journal
Volume73
Issue number3
DOIs
Publication statusPublished - Mar 1 2009
Externally publishedYes

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Adipokines
Lipoproteins
Insulin Resistance
Adipose Tissue
Body Mass Index
Leptin
Body Composition
HDL Cholesterol
Photon Absorptiometry
LDL Cholesterol
Epidemiologic Studies
Japan
Obesity
Students
Lipids
Population

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Cite this

Lipoprotein metabolism, insulin resistance, and adipocytokine levels in Japanese female adolescents with a normal body mass index and high body fat mass. / Kishimoto, Noriaki; Okita, Koichi; Takada, Shingo; Sakuma, Ichiro; Saijo, Yasuaki; Chiba, Hitoshi; Ishii, Kojiro; Kishi, Reiko; Tsutsui, Hiroyuki.

In: Circulation Journal, Vol. 73, No. 3, 01.03.2009, p. 534-539.

Research output: Contribution to journalArticle

Kishimoto, Noriaki ; Okita, Koichi ; Takada, Shingo ; Sakuma, Ichiro ; Saijo, Yasuaki ; Chiba, Hitoshi ; Ishii, Kojiro ; Kishi, Reiko ; Tsutsui, Hiroyuki. / Lipoprotein metabolism, insulin resistance, and adipocytokine levels in Japanese female adolescents with a normal body mass index and high body fat mass. In: Circulation Journal. 2009 ; Vol. 73, No. 3. pp. 534-539.
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