肝門部領域胆管癌術後の難治性細胆管炎に起因すると思われる肝不全に対し 抗菌薬動注療法が奏効した1 例

Translated title of the contribution: Liver failure caused by refractory cholangitis after operation for Hilar cholangiocarcinoma, which was treated with intra-arterial antibiotic therapy

Masataka Hayashi, Yasuhisa Mori, Takao Ohtsuka, Kohei Nakata, Yoshihiro Miyasaka, Yoshiki Asayama, Kazuhiro Koto, Masafumi Nakamura

Research output: Contribution to journalArticlepeer-review

Abstract

We present a 65-year-old man who underwent left hepatic trisegmentectomy and biliary reconstruction for hilar cholangiocarcinoma. Four months after the operation, serum total bilirubin level was elevated to 24.1 mg/dl. CT revealed a migrated biliary stent in the intrahepatic bile duct. The stent was successfully removed under percutaneous transhepatic approach; however, serum total bilirubin level did not decreased. The diagnosis of liver failure caused by refractory cholangitis was made and, intra-arterial antibiotic therapy using meropenem and ciprofloxacin was performed, and thereafter, the serum total bilirubin promptly decreased. This case report suggests that intra-arterial antibiotic therapy seems to be effective for liver failure caused by refractory cholangitis after major hepatectomy with biliary reconstruction.

Translated title of the contributionLiver failure caused by refractory cholangitis after operation for Hilar cholangiocarcinoma, which was treated with intra-arterial antibiotic therapy
Original languageJapanese
Pages (from-to)45-52
Number of pages8
JournalJapanese Journal of Gastroenterological Surgery
Volume52
Issue number1
DOIs
Publication statusPublished - 2019

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology

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