Liver metastasis from gallbladder carcinoma: Anatomic correlation with cholecystic venous drainage demonstrated by helical computed tomography during injection of contrast medium into the cholecystic artery

Kengo Yoshimitsu, Hiroshi Honda, Toshiro Kuroiwa, Hiroyuki Irie, Hitoshi Aibe, Tsuyoshi Tajima, Kazuo Chijiiwa, Mitsuo Shimada, Kouji Masuda

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    27 Citations (Scopus)

    Abstract

    BACKGROUND. The current study evaluated whether the sites of liver metastasis from gallbladder carcinoma are correlated with areas of cholecystic venous drainage (CVD) utilizing helical computed tomography (CT) during the injection of contrast medium into the cholecystic artery (cholecystic artery CT). METHODS. Cholecystic artery CT scans were performed in 26 patients with gallbladder carcinoma. Liver metastases were examined retrospectively in these patients on CT, and the sites of liver metastasis and CVD were compared closely. The patients were divided into concurrent (those who had metastasis at the time of cholecystic artery CT), early postoperative metastasis (those who developed metastasis within 6 months after surgery), and late postoperative metastasis (those who developed metastasis more than 6 months after surgery) groups. The frequency of metastasis related to CVD was compared between the three groups. RESULTS. A total of 32 metastases were identified in 11 patients, 21 of which were related to CVD. Six patients were included in the concurrent metastasis group; 18 of 20 tumors were found to be related closely to CVD. There were two patients in the early postoperative metastasis group; all three of the tumors detected were found to be closely related to CVD. Three patients were subclassified as being in the late postoperative metastasis group; none of the nine tumors detected appeared to be in areas associated with CVD. CONCLUSIONS. The sites of liver metastases were found to be well correlated with the areas with CVD, particularly in the concurrent and early postoperative metastasis groups. CVD may be a useful marker of potential areas of liver metastasis from gallbladder carcinoma, particularly in patients with early stage metastasis.

    Original languageEnglish
    Pages (from-to)340-348
    Number of pages9
    JournalCancer
    Volume92
    Issue number2
    DOIs
    Publication statusPublished - Jul 15 2001

    All Science Journal Classification (ASJC) codes

    • Oncology
    • Cancer Research

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