Living donor liver transplantation in a patient with giant hepatic hemangioma complicated by Kasabach-Merritt syndrome: Report of a case

Makoto Meguro, Yuji Soejima, Akinobu Taketomi, Toru Ikegami, Yo Ichi Yamashita, Noboru Harada, Shinji Itoh, Koichi Hirata, Yoshihiko Maehara

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Abstract

We herein present a case of unresectable giant hepatic hemangiomas with Kasabach-Merritt syndrome which was successfully treated by living donor liver transplantation using a left lobe graft. The patient was a 45-year-old woman who complained of abdominal distension. Two sessions of transarterial embolization were performed, but failed to reduce the size of the tumor. The hepatic tumors were thus judged untreatable and the only option for a cure was to offer living donor liver transplantation, because of the tumor size, its location, and the association with Kasabach-Merritt syndrome. A left lobe graft with the middle hepatic vein donated by her 47-year-old brother was transplanted under venovenous bypass. The postoperative course of the recipient was complicated by small-for-size graft syndrome, which developed after episodes of acute cellular rejection on postoperative day 8 and sepsis on day 31. The patient successfully recovered from the complications and was discharged on day 72, and she remains well at 10 months after transplantation. In conclusion, living donor liver transplantation was found to be an effective option for the treatment of a patient with unresectable giant hepatic hemangiomas complicated by Kasabach-Merritt syndrome.

Original languageEnglish
Pages (from-to)463-468
Number of pages6
JournalSurgery today
Volume38
Issue number5
DOIs
Publication statusPublished - May 1 2008

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Kasabach-Merritt Syndrome
Living Donors
Hemangioma
Liver Transplantation
Transplants
Liver
Neoplasms
Hepatic Veins
Siblings
Sepsis
Transplantation
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

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Living donor liver transplantation in a patient with giant hepatic hemangioma complicated by Kasabach-Merritt syndrome : Report of a case. / Meguro, Makoto; Soejima, Yuji; Taketomi, Akinobu; Ikegami, Toru; Yamashita, Yo Ichi; Harada, Noboru; Itoh, Shinji; Hirata, Koichi; Maehara, Yoshihiko.

In: Surgery today, Vol. 38, No. 5, 01.05.2008, p. 463-468.

Research output: Contribution to journalArticle

Meguro, Makoto ; Soejima, Yuji ; Taketomi, Akinobu ; Ikegami, Toru ; Yamashita, Yo Ichi ; Harada, Noboru ; Itoh, Shinji ; Hirata, Koichi ; Maehara, Yoshihiko. / Living donor liver transplantation in a patient with giant hepatic hemangioma complicated by Kasabach-Merritt syndrome : Report of a case. In: Surgery today. 2008 ; Vol. 38, No. 5. pp. 463-468.
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