Living donor liver transplantation using dual grafts from two donors: A feasible option to overcome small-for-size graft problems?

Y. Soejima, A. Taketomi, T. Ikegami, T. Yoshizumi, H. Uchiyama, Y. Yamashita, M. Meguro, N. Harada, M. Shimada, Y. Maehara

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Living donor liver transplantation (LDLT) between adults inevitably implies two potential risks associated with a small-for-size graft for the recipient and small remnant liver for the donor. To overcome these problems, LDLT using dual grafts from two independent donors can be a solution, in which sufficient graft volume can be obtained while preserving donor safety. We present a case of LDLT that was managed successfully by using right and left lobe dual grafts from two donors. The recipient was a large-size male with hepatitis C cirrhosis complicated by multiple hepatocellular carcinomas (HCCs). The first donor donated a right lobe graft and the second donor donated a left lobe plus caudate lobe graft with the middle hepatic vein. Graft function was excellent throughout the course without evidence of small-for-size syndrome. In conclusion, LDLT using dual grafts can be justified in a selected case to avoid small-for-size graft problems without increasing independent donor risks.

Original languageEnglish
Pages (from-to)887-892
Number of pages6
JournalAmerican Journal of Transplantation
Volume8
Issue number4
DOIs
Publication statusPublished - Apr 2008

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

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