Local supply of reactive oxygen species into a tissue model by atmospheric-pressure plasma-jet exposure

Toshiyuki Kawasaki, Fumiaki Mitsugi, Kazunori Koga, Masaharu Shiratani

Research output: Contribution to journalArticle

Abstract

The supply of reactive oxygen species (ROSs) into a tissue by plasmas must be controlled for the safe and effective use of plasma technologies in biomedical applications. In this study, the two-dimensional distributions of ROSs after passing through an agarose tissue model by the plasma-jet exposures were visualized using a KI-starch gel reagent to evaluate the local ROS supply. Partial ROS supply on the tissue model surface induced the local ROS supply in a pointlike shape just under the plasma-exposed spot. The O3-containing gas exposure without direct plasma contact could not induce the local ROS supply. Therefore, the local ROS supply was assumed to be induced by plasma-specific effects. However, the results also indicated that the plasma jet coming in direct contact with the tissue model surface did not necessarily induce the local ROS supply. The effects of the tissue model thickness on the local ROS supply were also studied; the local ROS supply could penetrate to a depth of 2 mm in the tissue model under the given experimental conditions.

Original languageEnglish
Article number213303
JournalJournal of Applied Physics
Volume125
Issue number21
DOIs
Publication statusPublished - Jun 7 2019

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plasma jets
atmospheric pressure
oxygen
starches
reagents
gels
gases

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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Local supply of reactive oxygen species into a tissue model by atmospheric-pressure plasma-jet exposure. / Kawasaki, Toshiyuki; Mitsugi, Fumiaki; Koga, Kazunori; Shiratani, Masaharu.

In: Journal of Applied Physics, Vol. 125, No. 21, 213303, 07.06.2019.

Research output: Contribution to journalArticle

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