Localization of brain activation by umami taste in humans

Yuko Nakamura, Tazuko K. Goto, Kenji Tokumori, Takashi Yoshiura, Koji Kobayashi, Yasuhiko Nakamura, Hiroshi Honda, Yuzo Ninomiya, Kazunori Yoshiura

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

There are no credible data to support the notion that individual taste qualities have dedicated pathways leading from the tongue to the end of the pathway in the brain. Moreover, the insular cortex is activated not only by taste but also by non-taste information from oral stimuli. These responses are invariably excitatory, and it is difficult to determine whether they are sensory, motor, or proprioceptive in origin. Furthermore, umami is a more unfamiliar and complex taste than other basic tastes. Considering these issues, it may be effective to minimize somatosensory stimuli, oral movement, and psychological effects in a neuroimaging study to elicit cerebral activity by pure umami on the human tongue. For this purpose, we developed an original taste delivery system for functional magnetic resonance imaging (fMRI) studies for umami. Then, we compared the results produced by two authorized models, namely, the block design model and event-related design model, to decide the appropriate model for detecting activation by umami. Activation by the umami taste was well localized in the insular cortex using our new system and block design model analysis. The peaks of the activated areas in the middle insular cortex by umami were very close to another prototypical taste quality (salty). Although we have to carefully interpret the perceiving intensities and brain activations by taste from different sessions, this study design might be effective for detecting the accession area in the cortex of pure umami taste on the tongue.

Original languageEnglish
Pages (from-to)18-29
Number of pages12
JournalBrain Research
Volume1406
DOIs
Publication statusPublished - Aug 11 2011

Fingerprint

Brain
Tongue
Cerebral Cortex
Neuroimaging
Magnetic Resonance Imaging
Psychology

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Cite this

Nakamura, Y., Goto, T. K., Tokumori, K., Yoshiura, T., Kobayashi, K., Nakamura, Y., ... Yoshiura, K. (2011). Localization of brain activation by umami taste in humans. Brain Research, 1406, 18-29. https://doi.org/10.1016/j.brainres.2011.06.029

Localization of brain activation by umami taste in humans. / Nakamura, Yuko; Goto, Tazuko K.; Tokumori, Kenji; Yoshiura, Takashi; Kobayashi, Koji; Nakamura, Yasuhiko; Honda, Hiroshi; Ninomiya, Yuzo; Yoshiura, Kazunori.

In: Brain Research, Vol. 1406, 11.08.2011, p. 18-29.

Research output: Contribution to journalArticle

Nakamura, Y, Goto, TK, Tokumori, K, Yoshiura, T, Kobayashi, K, Nakamura, Y, Honda, H, Ninomiya, Y & Yoshiura, K 2011, 'Localization of brain activation by umami taste in humans', Brain Research, vol. 1406, pp. 18-29. https://doi.org/10.1016/j.brainres.2011.06.029
Nakamura Y, Goto TK, Tokumori K, Yoshiura T, Kobayashi K, Nakamura Y et al. Localization of brain activation by umami taste in humans. Brain Research. 2011 Aug 11;1406:18-29. https://doi.org/10.1016/j.brainres.2011.06.029
Nakamura, Yuko ; Goto, Tazuko K. ; Tokumori, Kenji ; Yoshiura, Takashi ; Kobayashi, Koji ; Nakamura, Yasuhiko ; Honda, Hiroshi ; Ninomiya, Yuzo ; Yoshiura, Kazunori. / Localization of brain activation by umami taste in humans. In: Brain Research. 2011 ; Vol. 1406. pp. 18-29.
@article{9db601466deb4c62be042258222b38ed,
title = "Localization of brain activation by umami taste in humans",
abstract = "There are no credible data to support the notion that individual taste qualities have dedicated pathways leading from the tongue to the end of the pathway in the brain. Moreover, the insular cortex is activated not only by taste but also by non-taste information from oral stimuli. These responses are invariably excitatory, and it is difficult to determine whether they are sensory, motor, or proprioceptive in origin. Furthermore, umami is a more unfamiliar and complex taste than other basic tastes. Considering these issues, it may be effective to minimize somatosensory stimuli, oral movement, and psychological effects in a neuroimaging study to elicit cerebral activity by pure umami on the human tongue. For this purpose, we developed an original taste delivery system for functional magnetic resonance imaging (fMRI) studies for umami. Then, we compared the results produced by two authorized models, namely, the block design model and event-related design model, to decide the appropriate model for detecting activation by umami. Activation by the umami taste was well localized in the insular cortex using our new system and block design model analysis. The peaks of the activated areas in the middle insular cortex by umami were very close to another prototypical taste quality (salty). Although we have to carefully interpret the perceiving intensities and brain activations by taste from different sessions, this study design might be effective for detecting the accession area in the cortex of pure umami taste on the tongue.",
author = "Yuko Nakamura and Goto, {Tazuko K.} and Kenji Tokumori and Takashi Yoshiura and Koji Kobayashi and Yasuhiko Nakamura and Hiroshi Honda and Yuzo Ninomiya and Kazunori Yoshiura",
year = "2011",
month = "8",
day = "11",
doi = "10.1016/j.brainres.2011.06.029",
language = "English",
volume = "1406",
pages = "18--29",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",

}

TY - JOUR

T1 - Localization of brain activation by umami taste in humans

AU - Nakamura, Yuko

AU - Goto, Tazuko K.

AU - Tokumori, Kenji

AU - Yoshiura, Takashi

AU - Kobayashi, Koji

AU - Nakamura, Yasuhiko

AU - Honda, Hiroshi

AU - Ninomiya, Yuzo

AU - Yoshiura, Kazunori

PY - 2011/8/11

Y1 - 2011/8/11

N2 - There are no credible data to support the notion that individual taste qualities have dedicated pathways leading from the tongue to the end of the pathway in the brain. Moreover, the insular cortex is activated not only by taste but also by non-taste information from oral stimuli. These responses are invariably excitatory, and it is difficult to determine whether they are sensory, motor, or proprioceptive in origin. Furthermore, umami is a more unfamiliar and complex taste than other basic tastes. Considering these issues, it may be effective to minimize somatosensory stimuli, oral movement, and psychological effects in a neuroimaging study to elicit cerebral activity by pure umami on the human tongue. For this purpose, we developed an original taste delivery system for functional magnetic resonance imaging (fMRI) studies for umami. Then, we compared the results produced by two authorized models, namely, the block design model and event-related design model, to decide the appropriate model for detecting activation by umami. Activation by the umami taste was well localized in the insular cortex using our new system and block design model analysis. The peaks of the activated areas in the middle insular cortex by umami were very close to another prototypical taste quality (salty). Although we have to carefully interpret the perceiving intensities and brain activations by taste from different sessions, this study design might be effective for detecting the accession area in the cortex of pure umami taste on the tongue.

AB - There are no credible data to support the notion that individual taste qualities have dedicated pathways leading from the tongue to the end of the pathway in the brain. Moreover, the insular cortex is activated not only by taste but also by non-taste information from oral stimuli. These responses are invariably excitatory, and it is difficult to determine whether they are sensory, motor, or proprioceptive in origin. Furthermore, umami is a more unfamiliar and complex taste than other basic tastes. Considering these issues, it may be effective to minimize somatosensory stimuli, oral movement, and psychological effects in a neuroimaging study to elicit cerebral activity by pure umami on the human tongue. For this purpose, we developed an original taste delivery system for functional magnetic resonance imaging (fMRI) studies for umami. Then, we compared the results produced by two authorized models, namely, the block design model and event-related design model, to decide the appropriate model for detecting activation by umami. Activation by the umami taste was well localized in the insular cortex using our new system and block design model analysis. The peaks of the activated areas in the middle insular cortex by umami were very close to another prototypical taste quality (salty). Although we have to carefully interpret the perceiving intensities and brain activations by taste from different sessions, this study design might be effective for detecting the accession area in the cortex of pure umami taste on the tongue.

UR - http://www.scopus.com/inward/record.url?scp=79960845610&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960845610&partnerID=8YFLogxK

U2 - 10.1016/j.brainres.2011.06.029

DO - 10.1016/j.brainres.2011.06.029

M3 - Article

VL - 1406

SP - 18

EP - 29

JO - Brain Research

JF - Brain Research

SN - 0006-8993

ER -