Localization of the primary taste cortex by contrasting passive and attentive conditions

Yuko Nakamura, Kenji Tokumori, Hiroki C. Tanabe, Takashi Yoshiura, Koji Kobayashi, Yasuhiko Nakamura, Hiroshi Honda, Kazunori Yoshiura, Tazuko K. Goto

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

The primary taste cortex is located in the insula. However, exactly where in the insula the human primary taste cortex is located remains a controversial issue. Human neuroimaging studies have shown prominent variation concerning the location of taste-responsive activation within the insula. A standard protocol for gustatory testing in neuroimaging studies has not been developed, which might underlie such variations. In order to localize the primary taste cortex in an fMRI experiment, we used a taste delivery system to suppress non-taste stimuli and psychological effects. Then, we compared brain response to taste solution during a passive tasting task condition and a taste quality identification task condition to verify whether this cognitive task affected the location of taste-responsive activation within the insula. To examine which part of insula is the primary taste area, we performed dynamic causal modeling (DCM) to verify the neural network of the taste coding-related region and random-effects Bayesian model selection (BMS) at the family level to reveal the optimal input region. Passive tasting resulted in activation of the right middle insula (MI), and the most favorable model selected by DCM analysis showed that taste effect directly influenced the MI. Additionally, BMS results at the family level suggested that the taste inputs entered into the MI. Taken together, our results suggest that the human primary taste cortex is located in the MI.

Original languageEnglish
Pages (from-to)185-197
Number of pages13
JournalExperimental Brain Research
Volume227
Issue number2
DOIs
Publication statusPublished - Jun 1 2013

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Neuroimaging
Magnetic Resonance Imaging
Psychology
Brain

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)

Cite this

Nakamura, Y., Tokumori, K., Tanabe, H. C., Yoshiura, T., Kobayashi, K., Nakamura, Y., ... Goto, T. K. (2013). Localization of the primary taste cortex by contrasting passive and attentive conditions. Experimental Brain Research, 227(2), 185-197. https://doi.org/10.1007/s00221-013-3499-z

Localization of the primary taste cortex by contrasting passive and attentive conditions. / Nakamura, Yuko; Tokumori, Kenji; Tanabe, Hiroki C.; Yoshiura, Takashi; Kobayashi, Koji; Nakamura, Yasuhiko; Honda, Hiroshi; Yoshiura, Kazunori; Goto, Tazuko K.

In: Experimental Brain Research, Vol. 227, No. 2, 01.06.2013, p. 185-197.

Research output: Contribution to journalArticle

Nakamura, Y, Tokumori, K, Tanabe, HC, Yoshiura, T, Kobayashi, K, Nakamura, Y, Honda, H, Yoshiura, K & Goto, TK 2013, 'Localization of the primary taste cortex by contrasting passive and attentive conditions', Experimental Brain Research, vol. 227, no. 2, pp. 185-197. https://doi.org/10.1007/s00221-013-3499-z
Nakamura Y, Tokumori K, Tanabe HC, Yoshiura T, Kobayashi K, Nakamura Y et al. Localization of the primary taste cortex by contrasting passive and attentive conditions. Experimental Brain Research. 2013 Jun 1;227(2):185-197. https://doi.org/10.1007/s00221-013-3499-z
Nakamura, Yuko ; Tokumori, Kenji ; Tanabe, Hiroki C. ; Yoshiura, Takashi ; Kobayashi, Koji ; Nakamura, Yasuhiko ; Honda, Hiroshi ; Yoshiura, Kazunori ; Goto, Tazuko K. / Localization of the primary taste cortex by contrasting passive and attentive conditions. In: Experimental Brain Research. 2013 ; Vol. 227, No. 2. pp. 185-197.
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