Localized chromophobe carcinomas treated by nephron-sparing surgery have excellent oncologic outcomes

members of the Kidney Cancer group of the CCAFU

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5 Citations (Scopus)


Objective To evaluate the oncologic outcomes of nephron-sparing surgery (NSS) for localized chromophobe renal cell carcinoma (cRCC). Material and methods We performed a multicenter international study involving the French Network for Research on Kidney Cancer (UroCCR) and 5 international teams. Data from 808 patients treated with NSS between 2004 and 2014 for non–clear cell RCCs were analyzed. Results We included 234 patients with cRCC. There were 123 (52.6%) females. Median age was 61 (23–88) years. Median tumor size was 3 (1–11) cm. A positive surgical margin was identified in 14 specimens (6%). Pathologic stages were T1, T2, and T3a in 202 (86.3%), 9 (3.8%), and 23 (9.8%) cases, respectively. After a mean follow-up of 46.6 ± 36 months, 2 (0.8%) patients experienced a local recurrence. No patient had metastatic progression, and no patient died from cancer. Three-years estimated cancer-free survival and cancer-specific survival were 99.1% and 100%, respectively. Conclusion Oncological results of NSS for localized cRCC are excellent. In this series, only 2 patients had a local recurrence, and no patient had metastatic progression or died from cancer.

Original languageEnglish
Pages (from-to)35.e15-35.e19
JournalUrologic Oncology: Seminars and Original Investigations
Issue number1
Publication statusPublished - Jan 1 2017

All Science Journal Classification (ASJC) codes

  • Oncology
  • Urology


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