Long-term cytotoxicities of various pesticides evaluated by albumin secretion of primary cultured rat hepatocytes

Kazuhiro Ichikawa, Yasuyuki Sakai, Akiyoshi Sakoda, Motoyuki Suzuki

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)

    Abstract

    Primary cultured rat hepatocytes were used to estimate the cytotoxicities of various pesticides. The index was based on the inhibition of albumin secretion. Cytotoxicities closely correlated to the octanol/water distribution of pesticides. This estimation could be more reliable on the estimation of toxic effects on human health.

    Original languageEnglish
    Pages (from-to)99-102
    Number of pages4
    JournalBiotechnology Techniques
    Volume10
    Issue number2
    DOIs
    Publication statusPublished - 1996

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Applied Microbiology and Biotechnology

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