Long-term cytotoxicities of various pesticides evaluated by albumin secretion of primary cultured rat hepatocytes

Kazuhiro Ichikawa, Yasuyuki Sakai, Akiyoshi Sakoda, Motoyuki Suzuki

    Research output: Contribution to journalArticle

    1 Citation (Scopus)

    Abstract

    Primary cultured rat hepatocytes were used to estimate the cytotoxicities of various pesticides. The index was based on the inhibition of albumin secretion. Cytotoxicities closely correlated to the octanol/water distribution of pesticides. This estimation could be more reliable on the estimation of toxic effects on human health.

    Original languageEnglish
    Pages (from-to)99-102
    Number of pages4
    JournalBiotechnology Techniques
    Volume10
    Issue number2
    DOIs
    Publication statusPublished - Jan 1 1996

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    Cytotoxicity
    Pesticides
    Rats
    Hepatocytes
    Albumins
    Octanols
    Poisons
    Health
    Water

    All Science Journal Classification (ASJC) codes

    • Biochemistry
    • Applied Microbiology and Biotechnology

    Cite this

    Long-term cytotoxicities of various pesticides evaluated by albumin secretion of primary cultured rat hepatocytes. / Ichikawa, Kazuhiro; Sakai, Yasuyuki; Sakoda, Akiyoshi; Suzuki, Motoyuki.

    In: Biotechnology Techniques, Vol. 10, No. 2, 01.01.1996, p. 99-102.

    Research output: Contribution to journalArticle

    Ichikawa, Kazuhiro ; Sakai, Yasuyuki ; Sakoda, Akiyoshi ; Suzuki, Motoyuki. / Long-term cytotoxicities of various pesticides evaluated by albumin secretion of primary cultured rat hepatocytes. In: Biotechnology Techniques. 1996 ; Vol. 10, No. 2. pp. 99-102.
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