Long-term hearing outcome after retrosigmoid removal of vestibular schwannoma

Akira Nakamizo, Megumu Mori, Daisuke Inoue, Toshiyuki Amano, Masahiro Mizoguchi, Koji Yoshimoto, Tomio Sasaki

Research output: Contribution to journalArticle

10 Citations (Scopus)


Although many investigators have reported the hearing function in the immediate postoperative period in patients with vestibular schwannoma (VS), little is known about the long-term outcomes of the postoperative hearing. The aim of this study was to analyze the long-term hearing outcomes at a mean followup of 5 years in patients with unilateral VS treated via the retrosigmoid approach. Twenty-four patients with immediate postoperative serviceable hearing who underwent repeated audiogram or phone interview were included in this study. During the mean follow-up period (68.8 ± 30.2 months, range 14-123 months), serviceable hearing was preserved in 20 out of the 24 patients (83%). Pure tone average (PTA) was reevaluated within 6 months in seven patients. In the two patients whose PTA deteriorated ≥ 5 dB in 6 months after surgery, their PTA worsened ≥ 15 dB compared to the immediate postoperative PTA. In the remaining five patients whose PTA deteriorated < 5 dB in 6 months after surgery, PTA was maintained within a 15-dB deterioration at the final follow-up (p = 0.04, Fisher's exact test). According to Kaplan- Meier survival plots, the 5-year or 7-year preservation rate of serviceable hearing was 86.2% or 71.8%, respectively. Further study will be needed to clarify the mechanism underlying the long-term decline of serviceable hearing; however, the deterioration of PTA in the early postoperative period may help to predict the long-term outcomes of hearing.

Original languageEnglish
Pages (from-to)688-694
Number of pages7
JournalNeurologia medico-chirurgica
Issue number10
Publication statusPublished - 2013

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Long-term hearing outcome after retrosigmoid removal of vestibular schwannoma'. Together they form a unique fingerprint.

  • Cite this