Long-term local control of recurrent adenoid cystic carcinoma in the parotid gland with radiotherapy and intraarterial infusion chemotherapy

Koutarou Terashima, Yoshiyuki Shioyama, Katsumasa Nakamura, Saiji Ohga, Satoshi Nomoto, Toshihiro Yamaguchi, Takashi Toba, Tadamasa Yoshitake, Hidetake Yabuuchi, Torahiko Nakashima, Hiromi Terashima, Hiroshi Honda

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Abstract

We report a case of postoperative recurrence of adenoid cystic carcinoma in the left parotid gland treated with radiotherapy and arterial infusion chemotherapy. A 52-year-old woman had a history of surgical resection for an adenoid cystic carcinoma arising from the left parotid gland 25 years before. Despite two reoperations for local recurrence after the initial surgery, she had a third local recurrence in the remnant of the left parotid gland. The patient was treated with a concurrent combination of radiotherapy (60Gy/30F) and intraarterial infusion chemotherapy with carboplatin (750mg/30 days) from which she obtained a complete response. The patient has remained free of local progression 54 months after treatment. Radiotherapy and arterial infusion chemotherapy is effective treatment for local recurrence of adenoid cystic carcinoma in the head and neck.

Original languageEnglish
Pages (from-to)287-291
Number of pages5
JournalRadiation Medicine - Medical Imaging and Radiation Oncology
Volume24
Issue number4
DOIs
Publication statusPublished - May 1 2006

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All Science Journal Classification (ASJC) codes

  • Radiation
  • Radiology Nuclear Medicine and imaging
  • Oncology

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