Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma

Fumihiro Shoji, Riichiroh Maruyama, Tatsuro Okamoto, Jiro Ikeda, Tomomi Nakamura, Hiroshi Wataya, Yukito Ichinose

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not usually effective. Case presentation: We herein report a patient with pulmonary giant cell carcinoma with stage IV disease in whom aggressive multi-modality therapy resulted in a long-term survival. A 51-year-old male underwent an emergent operation with a partial resection of small intestinal metastases due to bleeding from the tumor. The patient also underwent a left pneumonectomy due to hemothorax as a result of the rapid growth of the primary tumor. Thereafter, two different regimens of chemotherapy and a partial resection for other site of small intestinal metastases and a splenectomy for splenic metastases were performed. The patient is presently doing well without any evidence of recurrence for 3 years after the initial operation. Conclusion: This is a first report of a rare case with stage IV pulmonary giant cell carcinoma who has survived long-term after undergoing aggressive surgical treatment and chemotherapy.

Original languageEnglish
Article number32
JournalWorld Journal of Surgical Oncology
Volume3
DOIs
Publication statusPublished - Jun 2 2005

Fingerprint

Giant Cell Carcinoma
Drug Therapy
Lung
Survival
Neoplasm Metastasis
Hemothorax
Neoplasms
Pneumonectomy
Splenectomy
Hemorrhage
Recurrence
Therapeutics
Growth

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma. / Shoji, Fumihiro; Maruyama, Riichiroh; Okamoto, Tatsuro; Ikeda, Jiro; Nakamura, Tomomi; Wataya, Hiroshi; Ichinose, Yukito.

In: World Journal of Surgical Oncology, Vol. 3, 32, 02.06.2005.

Research output: Contribution to journalArticle

Shoji, Fumihiro ; Maruyama, Riichiroh ; Okamoto, Tatsuro ; Ikeda, Jiro ; Nakamura, Tomomi ; Wataya, Hiroshi ; Ichinose, Yukito. / Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma. In: World Journal of Surgical Oncology. 2005 ; Vol. 3.
@article{7dd436945ca94f10aa57738e3c1b563e,
title = "Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma",
abstract = "Background: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not usually effective. Case presentation: We herein report a patient with pulmonary giant cell carcinoma with stage IV disease in whom aggressive multi-modality therapy resulted in a long-term survival. A 51-year-old male underwent an emergent operation with a partial resection of small intestinal metastases due to bleeding from the tumor. The patient also underwent a left pneumonectomy due to hemothorax as a result of the rapid growth of the primary tumor. Thereafter, two different regimens of chemotherapy and a partial resection for other site of small intestinal metastases and a splenectomy for splenic metastases were performed. The patient is presently doing well without any evidence of recurrence for 3 years after the initial operation. Conclusion: This is a first report of a rare case with stage IV pulmonary giant cell carcinoma who has survived long-term after undergoing aggressive surgical treatment and chemotherapy.",
author = "Fumihiro Shoji and Riichiroh Maruyama and Tatsuro Okamoto and Jiro Ikeda and Tomomi Nakamura and Hiroshi Wataya and Yukito Ichinose",
year = "2005",
month = "6",
day = "2",
doi = "10.1186/1477-7819-3-32",
language = "English",
volume = "3",
journal = "World Journal of Surgical Oncology",
issn = "1477-7819",
publisher = "BioMed Central",

}

TY - JOUR

T1 - Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma

AU - Shoji, Fumihiro

AU - Maruyama, Riichiroh

AU - Okamoto, Tatsuro

AU - Ikeda, Jiro

AU - Nakamura, Tomomi

AU - Wataya, Hiroshi

AU - Ichinose, Yukito

PY - 2005/6/2

Y1 - 2005/6/2

N2 - Background: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not usually effective. Case presentation: We herein report a patient with pulmonary giant cell carcinoma with stage IV disease in whom aggressive multi-modality therapy resulted in a long-term survival. A 51-year-old male underwent an emergent operation with a partial resection of small intestinal metastases due to bleeding from the tumor. The patient also underwent a left pneumonectomy due to hemothorax as a result of the rapid growth of the primary tumor. Thereafter, two different regimens of chemotherapy and a partial resection for other site of small intestinal metastases and a splenectomy for splenic metastases were performed. The patient is presently doing well without any evidence of recurrence for 3 years after the initial operation. Conclusion: This is a first report of a rare case with stage IV pulmonary giant cell carcinoma who has survived long-term after undergoing aggressive surgical treatment and chemotherapy.

AB - Background: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not usually effective. Case presentation: We herein report a patient with pulmonary giant cell carcinoma with stage IV disease in whom aggressive multi-modality therapy resulted in a long-term survival. A 51-year-old male underwent an emergent operation with a partial resection of small intestinal metastases due to bleeding from the tumor. The patient also underwent a left pneumonectomy due to hemothorax as a result of the rapid growth of the primary tumor. Thereafter, two different regimens of chemotherapy and a partial resection for other site of small intestinal metastases and a splenectomy for splenic metastases were performed. The patient is presently doing well without any evidence of recurrence for 3 years after the initial operation. Conclusion: This is a first report of a rare case with stage IV pulmonary giant cell carcinoma who has survived long-term after undergoing aggressive surgical treatment and chemotherapy.

UR - http://www.scopus.com/inward/record.url?scp=27444441380&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=27444441380&partnerID=8YFLogxK

U2 - 10.1186/1477-7819-3-32

DO - 10.1186/1477-7819-3-32

M3 - Article

AN - SCOPUS:27444441380

VL - 3

JO - World Journal of Surgical Oncology

JF - World Journal of Surgical Oncology

SN - 1477-7819

M1 - 32

ER -