Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney

Yuhki Koga; Akinobu Matsuzaki; Aiko Suminoe; Miho Hatano; Yusuke Saito; Yoshiaki Kinoshita; Tatsuro Tajiri; Tomoaki Taguchi; Kenichi Kohashi; Yoshinao Oda; Masazumi Tsuneyoshi; Toshiro Hara

doi:10.1002/pbc.21958

Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney

Yuhki Koga, Akinobu Matsuzaki, Aiko Suminoe, Miho Hatano, Yusuke Saito, Yoshiaki Kinoshita, Tatsuro Tajiri, Tomoaki Taguchi, Kenichi Kohashi, Yoshinao Oda, Masazumi Tsuneyoshi, Toshiro Hara

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Abstract

A 5-month-old male with stage II malignant rhabdoid tumor of the kidney (MRTK) and a 24-month-old male with stage III MRTK were treated with surgical resection of tumors and chemotherapy of alternating ICE (ifosfamide, carboplatin, and etoposide) and VDC (vincristine, doxorubicin, and cyclophosphamide), followed by highdose chemotherapy using etoposide, carboplatin, and melphalan with autologous hematopoietic stem cell transplantation (SCT). Two patients have been alive without any evidence of disease for 30 and 37 months after diagnosis, respectively, and require no medication. Consolidation with SCT should be further studies for selected patients with high-risk MRTK.

Original language	English
Pages (from-to)	888-890
Number of pages	3
Journal	Pediatric Blood and Cancer
Volume	52
Issue number	7
DOIs	https://doi.org/10.1002/pbc.21958
Publication status	Published - Jul 1 2009

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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Koga, Y., Matsuzaki, A., Suminoe, A., Hatano, M., Saito, Y., Kinoshita, Y., Tajiri, T., Taguchi, T., Kohashi, K., Oda, Y., Tsuneyoshi, M., & Hara, T. (2009). Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney. Pediatric Blood and Cancer, 52(7), 888-890. https://doi.org/10.1002/pbc.21958

Koga, Y, Matsuzaki, A, Suminoe, A, Hatano, M, Saito, Y, Kinoshita, Y, Tajiri, T, Taguchi, T, Kohashi, K, Oda, Y, Tsuneyoshi, M & Hara, T 2009, 'Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney', Pediatric Blood and Cancer, vol. 52, no. 7, pp. 888-890. https://doi.org/10.1002/pbc.21958

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abstract = "A 5-month-old male with stage II malignant rhabdoid tumor of the kidney (MRTK) and a 24-month-old male with stage III MRTK were treated with surgical resection of tumors and chemotherapy of alternating ICE (ifosfamide, carboplatin, and etoposide) and VDC (vincristine, doxorubicin, and cyclophosphamide), followed by highdose chemotherapy using etoposide, carboplatin, and melphalan with autologous hematopoietic stem cell transplantation (SCT). Two patients have been alive without any evidence of disease for 30 and 37 months after diagnosis, respectively, and require no medication. Consolidation with SCT should be further studies for selected patients with high-risk MRTK.",

author = "Yuhki Koga and Akinobu Matsuzaki and Aiko Suminoe and Miho Hatano and Yusuke Saito and Yoshiaki Kinoshita and Tatsuro Tajiri and Tomoaki Taguchi and Kenichi Kohashi and Yoshinao Oda and Masazumi Tsuneyoshi and Toshiro Hara",

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AU - Koga, Yuhki

AU - Matsuzaki, Akinobu

AU - Suminoe, Aiko

AU - Hatano, Miho

AU - Saito, Yusuke

AU - Kinoshita, Yoshiaki

AU - Tajiri, Tatsuro

AU - Taguchi, Tomoaki

AU - Kohashi, Kenichi

AU - Oda, Yoshinao

AU - Tsuneyoshi, Masazumi

AU - Hara, Toshiro

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AB - A 5-month-old male with stage II malignant rhabdoid tumor of the kidney (MRTK) and a 24-month-old male with stage III MRTK were treated with surgical resection of tumors and chemotherapy of alternating ICE (ifosfamide, carboplatin, and etoposide) and VDC (vincristine, doxorubicin, and cyclophosphamide), followed by highdose chemotherapy using etoposide, carboplatin, and melphalan with autologous hematopoietic stem cell transplantation (SCT). Two patients have been alive without any evidence of disease for 30 and 37 months after diagnosis, respectively, and require no medication. Consolidation with SCT should be further studies for selected patients with high-risk MRTK.

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Long-term survival after autologous peripheral blood stem cell transplantation in two patients with malignant rhabdoid tumor of the kidney

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