[Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy].

Yujiro Tsuda, Shogo Kobayashi, Yoshito Tomimaru, Hirofumi Akita, Naoki Hama, Hiroshi Wada, Koichi Kawamoto, Hidetoshi Eguchi, Koji Umeshita, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

Research output: Contribution to journalArticle

Abstract

We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT). A 54-year-old man with severe liver cirrhosis was diagnosed as having HCC in segment 1 and 4 of the liver, with PVTT in the left branch. After 7 courses of FAIT, the main tumor and PVTT were no longer visible on enhanced computed tomography scans. However, recurrent HCC was detected in segment 4. Subsequently, the patient was treated with transarterial chemoembolization (TACE) after confirmation of portal blood flow. At 5 years after the initial treatment, the patient is alive without further recurrence of HCC. Therefore, even if patients have HCC with PVTT in the main branch and severe liver cirrhosis, long-term survival is possible by administration of a combination of FAIT and TACE.

Original languageEnglish
Pages (from-to)1804-1806
Number of pages3
JournalUnknown Journal
Volume40
Issue number12
Publication statusPublished - Nov 2013

Fingerprint

Portal Vein
tumor
Fluorouracil
Interferons
Hepatocellular Carcinoma
Thrombosis
Survival
Neoplasms
Liver Cirrhosis
Therapeutics
tomography
blood
Tomography
therapy
Recurrence
Liver

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

[Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy]. / Tsuda, Yujiro; Kobayashi, Shogo; Tomimaru, Yoshito; Akita, Hirofumi; Hama, Naoki; Wada, Hiroshi; Kawamoto, Koichi; Eguchi, Hidetoshi; Umeshita, Koji; Doki, Yuichiro; Mori, Masaki; Nagano, Hiroaki.

In: Unknown Journal, Vol. 40, No. 12, 11.2013, p. 1804-1806.

Research output: Contribution to journalArticle

Tsuda, Y, Kobayashi, S, Tomimaru, Y, Akita, H, Hama, N, Wada, H, Kawamoto, K, Eguchi, H, Umeshita, K, Doki, Y, Mori, M & Nagano, H 2013, '[Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy].', Unknown Journal, vol. 40, no. 12, pp. 1804-1806.
Tsuda, Yujiro ; Kobayashi, Shogo ; Tomimaru, Yoshito ; Akita, Hirofumi ; Hama, Naoki ; Wada, Hiroshi ; Kawamoto, Koichi ; Eguchi, Hidetoshi ; Umeshita, Koji ; Doki, Yuichiro ; Mori, Masaki ; Nagano, Hiroaki. / [Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy]. In: Unknown Journal. 2013 ; Vol. 40, No. 12. pp. 1804-1806.
@article{97270d72a34c47a59be14b5055e59d23,
title = "[Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy].",
abstract = "We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT). A 54-year-old man with severe liver cirrhosis was diagnosed as having HCC in segment 1 and 4 of the liver, with PVTT in the left branch. After 7 courses of FAIT, the main tumor and PVTT were no longer visible on enhanced computed tomography scans. However, recurrent HCC was detected in segment 4. Subsequently, the patient was treated with transarterial chemoembolization (TACE) after confirmation of portal blood flow. At 5 years after the initial treatment, the patient is alive without further recurrence of HCC. Therefore, even if patients have HCC with PVTT in the main branch and severe liver cirrhosis, long-term survival is possible by administration of a combination of FAIT and TACE.",
author = "Yujiro Tsuda and Shogo Kobayashi and Yoshito Tomimaru and Hirofumi Akita and Naoki Hama and Hiroshi Wada and Koichi Kawamoto and Hidetoshi Eguchi and Koji Umeshita and Yuichiro Doki and Masaki Mori and Hiroaki Nagano",
year = "2013",
month = "11",
language = "English",
volume = "40",
pages = "1804--1806",
journal = "Quaternary International",
issn = "1040-6182",
publisher = "Elsevier Limited",
number = "12",

}

TY - JOUR

T1 - [Long-term survival of a patient with hepatocellular carcinoma with portal vein tumor thrombus treated with interferon-α and 5-fluorouracil combination therapy].

AU - Tsuda, Yujiro

AU - Kobayashi, Shogo

AU - Tomimaru, Yoshito

AU - Akita, Hirofumi

AU - Hama, Naoki

AU - Wada, Hiroshi

AU - Kawamoto, Koichi

AU - Eguchi, Hidetoshi

AU - Umeshita, Koji

AU - Doki, Yuichiro

AU - Mori, Masaki

AU - Nagano, Hiroaki

PY - 2013/11

Y1 - 2013/11

N2 - We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT). A 54-year-old man with severe liver cirrhosis was diagnosed as having HCC in segment 1 and 4 of the liver, with PVTT in the left branch. After 7 courses of FAIT, the main tumor and PVTT were no longer visible on enhanced computed tomography scans. However, recurrent HCC was detected in segment 4. Subsequently, the patient was treated with transarterial chemoembolization (TACE) after confirmation of portal blood flow. At 5 years after the initial treatment, the patient is alive without further recurrence of HCC. Therefore, even if patients have HCC with PVTT in the main branch and severe liver cirrhosis, long-term survival is possible by administration of a combination of FAIT and TACE.

AB - We report a case of long-term survival of a patient with hepatocellular carcinoma( HCC) with portal vein tumor thrombus (PVTT) treated with fluorouracil arterial infusion and interferon therapy (FAIT). A 54-year-old man with severe liver cirrhosis was diagnosed as having HCC in segment 1 and 4 of the liver, with PVTT in the left branch. After 7 courses of FAIT, the main tumor and PVTT were no longer visible on enhanced computed tomography scans. However, recurrent HCC was detected in segment 4. Subsequently, the patient was treated with transarterial chemoembolization (TACE) after confirmation of portal blood flow. At 5 years after the initial treatment, the patient is alive without further recurrence of HCC. Therefore, even if patients have HCC with PVTT in the main branch and severe liver cirrhosis, long-term survival is possible by administration of a combination of FAIT and TACE.

UR - http://www.scopus.com/inward/record.url?scp=84897018563&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84897018563&partnerID=8YFLogxK

M3 - Article

C2 - 24393928

AN - SCOPUS:84897018563

VL - 40

SP - 1804

EP - 1806

JO - Quaternary International

JF - Quaternary International

SN - 1040-6182

IS - 12

ER -