[Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus].

Takuya Sakamoto, Shogo Kobayashi, Yoshito Tomimaru, Hiroshi Wada, Hirofumi Akita, Naoki Hama, Koichi Kawamoto, Hidetoshi Eguchi, Koji Umeshita, Yuichiro Doki, Masaki Mori, Hiroaki Nagano

Research output: Contribution to journalArticle

Abstract

A 59-year-old man was diagnosed as having hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) from the left branch to the main trunk and multiple liver tumors in the right lobe. He first underwent 8 courses of fluorouracil arterial infusion and interferon therapy( FAIT).The PVTT shrunk following combination therapy; however, the liver tumors were enlarged and metastasis was noted in the right adrenal gland. Treatment with sorafenib was initiated. Ten months later, additional reduction of PVTT was noted with no changes in the multiple liver tumors. After confirmation of sufficient portal flow, we performed transcatheter arterial chemoembolization (TACE).After having undergone, in total, 4 rounds of TACE with sorafenib, the patient underwent radiofrequency ablation( RFA) for the right adrenal gland metastasis. The patient is still alive, in good health. Our findings from this case suggest that, in some patients having advanced HCC with PVTT, long- term survival can be achieved when the intrahepatic lesions are controlled by various adequate therapies.

Original languageEnglish
Pages (from-to)1816-1818
Number of pages3
JournalUnknown Journal
Volume40
Issue number12
Publication statusPublished - Jan 1 2013

Fingerprint

Portal Vein
tumor
Hepatocellular Carcinoma
Thrombosis
Survival
Neoplasms
Adrenal Glands
Liver
Neoplasm Metastasis
Therapeutics
ablation
lesion
Fluorouracil
Interferons
Health
therapy

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

Sakamoto, T., Kobayashi, S., Tomimaru, Y., Wada, H., Akita, H., Hama, N., ... Nagano, H. (2013). [Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus]. Unknown Journal, 40(12), 1816-1818.

[Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus]. / Sakamoto, Takuya; Kobayashi, Shogo; Tomimaru, Yoshito; Wada, Hiroshi; Akita, Hirofumi; Hama, Naoki; Kawamoto, Koichi; Eguchi, Hidetoshi; Umeshita, Koji; Doki, Yuichiro; Mori, Masaki; Nagano, Hiroaki.

In: Unknown Journal, Vol. 40, No. 12, 01.01.2013, p. 1816-1818.

Research output: Contribution to journalArticle

Sakamoto, T, Kobayashi, S, Tomimaru, Y, Wada, H, Akita, H, Hama, N, Kawamoto, K, Eguchi, H, Umeshita, K, Doki, Y, Mori, M & Nagano, H 2013, '[Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus].', Unknown Journal, vol. 40, no. 12, pp. 1816-1818.
Sakamoto T, Kobayashi S, Tomimaru Y, Wada H, Akita H, Hama N et al. [Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus]. Unknown Journal. 2013 Jan 1;40(12):1816-1818.
Sakamoto, Takuya ; Kobayashi, Shogo ; Tomimaru, Yoshito ; Wada, Hiroshi ; Akita, Hirofumi ; Hama, Naoki ; Kawamoto, Koichi ; Eguchi, Hidetoshi ; Umeshita, Koji ; Doki, Yuichiro ; Mori, Masaki ; Nagano, Hiroaki. / [Long-term survival of a patient with multiple advanced hepatocellular carcinomas with portal vein tumor thrombus]. In: Unknown Journal. 2013 ; Vol. 40, No. 12. pp. 1816-1818.
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