Abstract
Objective: To evaluate the confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose screening CT with hybrid iterative reconstruction (IR). Methods: Simulated lesions (emphysema, mediastinal masses and interstitial pneumonia) in a chest phantom were scanned by a 320-row area detector CT. The scans were performed by 64-row and 160-row helical scans at various dose levels and were reconstructed by filtered back projection (FBP) and IR. Emphysema, honeycombing and reticular opacity were visually scored on a four-point scale by six thoracic radiologists. The ground-glass opacity as a percentage of total lung volume (%GGO), CT value and contrast-to-noise ratio (CNR) of mediastinal masses were calculated. These scores and values were compared between FBP and IR. Wilcoxon's signed-rank test was used (p<0.05). Interobserver agreements were evaluated by k statistics. Results: There were no significant differences in visual assessment. Interobserver agreement was almost perfect. CT values were almost equivalent between FBP and IR, whereas CNR with IR was significantly higher than that with FBP. %GGO significantly increased at low-dose levels with FBP; however, IR suppressed the elevation. Conclusion: The confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose CT screening were not degraded with hybrid IR compared with FBP. Advances in knowledge: Hybrid IR did not degrade the confidence ratings of diagnoses on visual assessment and differential diagnoses based on CT value of mediastinal masses, and it showed the advantage of higher GGO conspicuity at low-dose level. Radiologists can analyse images of hybrid IR alone on low-dose CT screening for lung cancer.
| Original language | English |
|---|---|
| Article number | 20150159 |
| Journal | British Journal of Radiology |
| Volume | 88 |
| Issue number | 1053 |
| DOIs | |
| Publication status | Published - Sep 1 2015 |
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All Science Journal Classification (ASJC) codes
- Radiology Nuclear Medicine and imaging
Cite this
Low-dose CT screening using hybrid iterative reconstruction : Confidence ratings of diagnoses of simulated lesions other than lung cancer. / Sakai, N.; Yabuuchi, Hidetake; Kondo, M.; Matsuo, Y.; Kamitani, Takeshi; Nagao, M.; Jinnouchi, M.; Yonezawa, M.; Kojima, T.; Yano, Y.; Honda, Hiroshi.
In: British Journal of Radiology, Vol. 88, No. 1053, 20150159, 01.09.2015.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Low-dose CT screening using hybrid iterative reconstruction
T2 - Confidence ratings of diagnoses of simulated lesions other than lung cancer
AU - Sakai, N.
AU - Yabuuchi, Hidetake
AU - Kondo, M.
AU - Matsuo, Y.
AU - Kamitani, Takeshi
AU - Nagao, M.
AU - Jinnouchi, M.
AU - Yonezawa, M.
AU - Kojima, T.
AU - Yano, Y.
AU - Honda, Hiroshi
PY - 2015/9/1
Y1 - 2015/9/1
N2 - Objective: To evaluate the confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose screening CT with hybrid iterative reconstruction (IR). Methods: Simulated lesions (emphysema, mediastinal masses and interstitial pneumonia) in a chest phantom were scanned by a 320-row area detector CT. The scans were performed by 64-row and 160-row helical scans at various dose levels and were reconstructed by filtered back projection (FBP) and IR. Emphysema, honeycombing and reticular opacity were visually scored on a four-point scale by six thoracic radiologists. The ground-glass opacity as a percentage of total lung volume (%GGO), CT value and contrast-to-noise ratio (CNR) of mediastinal masses were calculated. These scores and values were compared between FBP and IR. Wilcoxon's signed-rank test was used (p<0.05). Interobserver agreements were evaluated by k statistics. Results: There were no significant differences in visual assessment. Interobserver agreement was almost perfect. CT values were almost equivalent between FBP and IR, whereas CNR with IR was significantly higher than that with FBP. %GGO significantly increased at low-dose levels with FBP; however, IR suppressed the elevation. Conclusion: The confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose CT screening were not degraded with hybrid IR compared with FBP. Advances in knowledge: Hybrid IR did not degrade the confidence ratings of diagnoses on visual assessment and differential diagnoses based on CT value of mediastinal masses, and it showed the advantage of higher GGO conspicuity at low-dose level. Radiologists can analyse images of hybrid IR alone on low-dose CT screening for lung cancer.
AB - Objective: To evaluate the confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose screening CT with hybrid iterative reconstruction (IR). Methods: Simulated lesions (emphysema, mediastinal masses and interstitial pneumonia) in a chest phantom were scanned by a 320-row area detector CT. The scans were performed by 64-row and 160-row helical scans at various dose levels and were reconstructed by filtered back projection (FBP) and IR. Emphysema, honeycombing and reticular opacity were visually scored on a four-point scale by six thoracic radiologists. The ground-glass opacity as a percentage of total lung volume (%GGO), CT value and contrast-to-noise ratio (CNR) of mediastinal masses were calculated. These scores and values were compared between FBP and IR. Wilcoxon's signed-rank test was used (p<0.05). Interobserver agreements were evaluated by k statistics. Results: There were no significant differences in visual assessment. Interobserver agreement was almost perfect. CT values were almost equivalent between FBP and IR, whereas CNR with IR was significantly higher than that with FBP. %GGO significantly increased at low-dose levels with FBP; however, IR suppressed the elevation. Conclusion: The confidence ratings of diagnoses of simulated lesions other than lung cancer on low-dose CT screening were not degraded with hybrid IR compared with FBP. Advances in knowledge: Hybrid IR did not degrade the confidence ratings of diagnoses on visual assessment and differential diagnoses based on CT value of mediastinal masses, and it showed the advantage of higher GGO conspicuity at low-dose level. Radiologists can analyse images of hybrid IR alone on low-dose CT screening for lung cancer.
UR - http://www.scopus.com/inward/record.url?scp=84941710930&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84941710930&partnerID=8YFLogxK
U2 - 10.1259/bjr.20150159
DO - 10.1259/bjr.20150159
M3 - Article
C2 - 26153902
AN - SCOPUS:84941710930
VL - 88
JO - British Journal of Radiology
JF - British Journal of Radiology
SN - 0007-1285
IS - 1053
M1 - 20150159
ER -