Low Radiation Dose and High Image Quality of 320-Row Coronary Computed Tomography Angiography Using a Small Dose of Contrast Medium and Refined Scan Timing Prediction

Takashi Shirasaka, Michinobu Nagao, Yuzo Yamasaki, Tsukasa Kojima, Masatoshi Kondo, Hiroshi Hamasaki, Takeshi Kamitani, Toyoyuki Kato, Yoshiki Asayama

Research output: Contribution to journalArticle


OBJECTIVE: The aim of the study was to investigate the feasibility of coronary computed tomography (CT) angiography with a low kilovoltage peak scan and a refined scan timing prediction using a small contrast medium (CM) dose. METHODS: In protocol A, 120-kVp scanning and a standard CM dose were used. The scan timing was fixed. In protocol B, 80 kVp and a 60% CM dose were used. The scan timing was determined according to the interval from the CM arrival to the peak time in the ascending aorta. We measured the CT number and recorded the radiation dose. RESULTS: Higher CT numbers were observed in the left circumflex (proximal, P = 0.0235; middle, P = 0.0007; distal, P < 0.0001) in protocol B compared with protocol A. The radiation dose in protocol B was significantly lower than in protocol A (2.2 ± 0.9 vs 4.3 ± 1.7 mSv). CONCLUSIONS: Low-contrast, low-radiation dose, high-image quality coronary CT angiography can be performed with low kilovoltage peak scanning and a refined scan timing prediction.

Original languageEnglish
Pages (from-to)7-12
Number of pages6
JournalJournal of computer assisted tomography
Issue number1
Publication statusPublished - Jan 1 2020


All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

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