Lung adenocarcinoma with multiple pulmonary metastases completely responsive to combination chemotherapy with carboplatin and weekly paclitaxel--a case report

Teruyoshi Ishida, Makiko Tomiyasu, Hidenori Kohso, Takashi Iwanami, Toru Ikegami, Jin Okazaki, Yasunori Emi, Akinori Kido, Takahiro Ezaki

Research output: Contribution to journalArticle

Abstract

We report a case in which lung adenocarcinoma with multiple pulmonary metastases was completely responsive to combination chemotherapy with carboplatin (CBDCA) and weekly paclitaxel (TXL). CBDCA AUC = 5 (day 1) and TXL 75 mg/m2 (day 1, 8, 15) were infused over 1 hour after short premedication on an outpatient basis. Administration was continued for 3 weeks followed by 1 week rest. The patient was a 54-year-old woman who suffered from lung adenocarcinoma with mediastinal lymph node metastases, stage III A, and underwent complete resection. However, multiple pulmonary metastases were found 3 years after operation. On an outpatient treatment, she was treated with CBDCA combined with weekly TXL for 6 cycles. The multiple pulmonary metastases had completely disappeared after 2 cycles and CEA decreased to within normal limit after 5 cycles. The toxic events were anemia (grade 2), leucocytopenia (grade 2) and alopecia (grade 3). No major adverse effects such as hypersensitivity reaction or peripheral neuropathy were observed.

Original languageEnglish
Pages (from-to)1313-1316
Number of pages4
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume30
Issue number9
Publication statusPublished - Jan 1 2003
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Lung adenocarcinoma with multiple pulmonary metastases completely responsive to combination chemotherapy with carboplatin and weekly paclitaxel--a case report'. Together they form a unique fingerprint.

  • Cite this

    Ishida, T., Tomiyasu, M., Kohso, H., Iwanami, T., Ikegami, T., Okazaki, J., Emi, Y., Kido, A., & Ezaki, T. (2003). Lung adenocarcinoma with multiple pulmonary metastases completely responsive to combination chemotherapy with carboplatin and weekly paclitaxel--a case report. Gan to kagaku ryoho. Cancer & chemotherapy, 30(9), 1313-1316.