Magnetic nanoparticle imaging using cooled-Cu/HTS-superconductor pickup coils

T. Morishige, T. Mihaya, T. Miyazai, Takashi Yoshida, M. Matsuo, Keiji Enpuku

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

We developed a highly sensitive measurement system of AC magnetic fields for magnetic nanoparticle imaging (MPI). First, we developed a detection system using pickup coils made of cooled Cu wire and HTS tape. The pickup coils were connected to a resonant capacitor in order to enhance the signal voltage generated in the pickup coils. The magnetic field noise at the resonant frequency was as low as 90 fT/Hz1/2 and 13 fT/Hz1/2 for the Cu and HTS coils, respectively. Next, we demonstrated the detection of nanoparticles using third-harmonic signal generated by the nonlinear magnetization of nanoparticles. An excitation field having a frequency of 1 kHz and an amplitude of 1.6 mT was applied to the magnetic particles and the third harmonic signal at 3 kHz was detected in order to reduce the interference from the excitation field. We demonstrated the detection of 0.1 mg of magnetic nanoparticles. We obtained a clear contour map of the magnetic field from the particles, and could detect the particles located as far as 100 mm under the pickup coil.

Original languageEnglish
Title of host publication2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013
DOIs
Publication statusPublished - Oct 15 2013
Event2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013 - Cambridge, MA, United States
Duration: Jul 7 2013Jul 11 2013

Other

Other2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013
CountryUnited States
CityCambridge, MA
Period7/7/137/11/13

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering

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    Morishige, T., Mihaya, T., Miyazai, T., Yoshida, T., Matsuo, M., & Enpuku, K. (2013). Magnetic nanoparticle imaging using cooled-Cu/HTS-superconductor pickup coils. In 2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013 [6604312] https://doi.org/10.1109/ISEC.2013.6604312