TY - GEN
T1 - Magnetic nanoparticle imaging using cooled-Cu/HTS-superconductor pickup coils
AU - Morishige, T.
AU - Mihaya, T.
AU - Miyazai, T.
AU - Yoshida, T.
AU - Matsuo, M.
AU - Enpuku, K.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2013
Y1 - 2013
N2 - We developed a highly sensitive measurement system of AC magnetic fields for magnetic nanoparticle imaging (MPI). First, we developed a detection system using pickup coils made of cooled Cu wire and HTS tape. The pickup coils were connected to a resonant capacitor in order to enhance the signal voltage generated in the pickup coils. The magnetic field noise at the resonant frequency was as low as 90 fT/Hz1/2 and 13 fT/Hz1/2 for the Cu and HTS coils, respectively. Next, we demonstrated the detection of nanoparticles using third-harmonic signal generated by the nonlinear magnetization of nanoparticles. An excitation field having a frequency of 1 kHz and an amplitude of 1.6 mT was applied to the magnetic particles and the third harmonic signal at 3 kHz was detected in order to reduce the interference from the excitation field. We demonstrated the detection of 0.1 mg of magnetic nanoparticles. We obtained a clear contour map of the magnetic field from the particles, and could detect the particles located as far as 100 mm under the pickup coil.
AB - We developed a highly sensitive measurement system of AC magnetic fields for magnetic nanoparticle imaging (MPI). First, we developed a detection system using pickup coils made of cooled Cu wire and HTS tape. The pickup coils were connected to a resonant capacitor in order to enhance the signal voltage generated in the pickup coils. The magnetic field noise at the resonant frequency was as low as 90 fT/Hz1/2 and 13 fT/Hz1/2 for the Cu and HTS coils, respectively. Next, we demonstrated the detection of nanoparticles using third-harmonic signal generated by the nonlinear magnetization of nanoparticles. An excitation field having a frequency of 1 kHz and an amplitude of 1.6 mT was applied to the magnetic particles and the third harmonic signal at 3 kHz was detected in order to reduce the interference from the excitation field. We demonstrated the detection of 0.1 mg of magnetic nanoparticles. We obtained a clear contour map of the magnetic field from the particles, and could detect the particles located as far as 100 mm under the pickup coil.
UR - http://www.scopus.com/inward/record.url?scp=84885202978&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885202978&partnerID=8YFLogxK
U2 - 10.1109/ISEC.2013.6604312
DO - 10.1109/ISEC.2013.6604312
M3 - Conference contribution
AN - SCOPUS:84885202978
SN - 9781467363716
T3 - 2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013
BT - 2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013
T2 - 2013 IEEE 14th InternationalSuperconductive Electronics Conference, ISEC 2013
Y2 - 7 July 2013 through 11 July 2013
ER -