Magnetic parameters evaluation of magnetic nanoparticles for use in biomedical applications

Ahmed L. Elrefai, Takashi Yoshida, Keiji Enpuku

Research output: Contribution to journalArticle

Abstract

We present a procedure for the comprehensive evaluation of parameters of magnetic nanoparticles (MNPs), such as saturation magnetization, core-size distribution, anisotropy energy constant, and characteristic time for Néel relaxation for use in biomedical applications and fundamental MNPs research. The static magnetization curve of suspended and immobilized MNP samples and the AC susceptibility of immobilized samples were used for the evaluation of these parameters. The magnetic properties reconstructed from the obtained parameters agreed with the experimental results, indicating the accuracy of the estimation procedure. Using the procedure, the parameters of the commercial Resovist MNP sample were evaluated. Then, the Resovist sample was magnetically fractionated into two MNP samples with large and small core sizes, and the parameters of the two fractionated samples were evaluated. It was demonstrated that the parameters of the Resovist sample are given by the volume-weighted average for those of the fractionated samples.

LanguageEnglish
Pages522-527
Number of pages6
JournalJournal of Magnetism and Magnetic Materials
Volume474
DOIs
Publication statusPublished - Mar 15 2019

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Nanomagnetics
Medical applications
Saturation magnetization
Magnetic susceptibility
Anisotropy
Nanoparticles
magnetic permeability
nanoparticles
anisotropy
evaluation
Magnetization
Magnetic properties
magnetization
alternating current
ferumoxides
magnetic properties
saturation

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics

Cite this

Magnetic parameters evaluation of magnetic nanoparticles for use in biomedical applications. / Elrefai, Ahmed L.; Yoshida, Takashi; Enpuku, Keiji.

In: Journal of Magnetism and Magnetic Materials, Vol. 474, 15.03.2019, p. 522-527.

Research output: Contribution to journalArticle

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