Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gastaut syndrome

Hideaki Ishibashi, Takato Morioka, Hiroshi Shigeto, Tomoya Yamamoto, Shunji Nishio, Masashi Fukui

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

We analyzed the preoperative and postoperative interictal magnetoencephalographic (MEG) patterns in a 32-year-old woman with Lennox- Gastaut syndrome who underwent an anterior corpus callosotomy (CC). A 37- channel biomagnetometer was used for the simultaneous recording of electroencephalogram (EEG) and MEG. Preoperatively, interictal EEG demonstrated a bilaterally synchronous spike and slow wave bursts with a maximum amplitude on the bifrontal region. The waveforms of the MEG were similar but did not completely correspond to those of the EEG. The estimated equivalent current dipoles (ECDs) originating from bilaterally synchronous paroxysmal discharges formed a dense cluster on the bilateral frontal lobes, especially on the deep midfrontal region. After anterior CC, MEG disclosed a marked reduction of the number of ECDs. The preoperative MEG patterns were thought to be representative of interhemispheric synchrony as a large dipole orientation, and these MEG paterns were partly disrupted by anterior CC.

Original languageEnglish
Pages (from-to)202-207
Number of pages6
JournalJournal of Epilepsy
Volume11
Issue number4
DOIs
Publication statusPublished - Jul 1 1998

Fingerprint

Electroencephalography
Frontal Lobe
Drug Resistant Epilepsy
Lennox Gastaut Syndrome

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Clinical Neurology

Cite this

Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gastaut syndrome. / Ishibashi, Hideaki; Morioka, Takato; Shigeto, Hiroshi; Yamamoto, Tomoya; Nishio, Shunji; Fukui, Masashi.

In: Journal of Epilepsy, Vol. 11, No. 4, 01.07.1998, p. 202-207.

Research output: Contribution to journalArticle

Ishibashi, Hideaki ; Morioka, Takato ; Shigeto, Hiroshi ; Yamamoto, Tomoya ; Nishio, Shunji ; Fukui, Masashi. / Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gastaut syndrome. In: Journal of Epilepsy. 1998 ; Vol. 11, No. 4. pp. 202-207.
@article{facb6b68714e4f82b14c8809d1cf3f26,
title = "Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gastaut syndrome",
abstract = "We analyzed the preoperative and postoperative interictal magnetoencephalographic (MEG) patterns in a 32-year-old woman with Lennox- Gastaut syndrome who underwent an anterior corpus callosotomy (CC). A 37- channel biomagnetometer was used for the simultaneous recording of electroencephalogram (EEG) and MEG. Preoperatively, interictal EEG demonstrated a bilaterally synchronous spike and slow wave bursts with a maximum amplitude on the bifrontal region. The waveforms of the MEG were similar but did not completely correspond to those of the EEG. The estimated equivalent current dipoles (ECDs) originating from bilaterally synchronous paroxysmal discharges formed a dense cluster on the bilateral frontal lobes, especially on the deep midfrontal region. After anterior CC, MEG disclosed a marked reduction of the number of ECDs. The preoperative MEG patterns were thought to be representative of interhemispheric synchrony as a large dipole orientation, and these MEG paterns were partly disrupted by anterior CC.",
author = "Hideaki Ishibashi and Takato Morioka and Hiroshi Shigeto and Tomoya Yamamoto and Shunji Nishio and Masashi Fukui",
year = "1998",
month = "7",
day = "1",
doi = "10.1016/S0896-6974(98)00018-8",
language = "English",
volume = "11",
pages = "202--207",
journal = "Epilepsy Research",
issn = "0920-1211",
publisher = "Elsevier",
number = "4",

}

TY - JOUR

T1 - Magnetoencephalographic evaluation of anterior corpus callosotomy for intractable epilepsy in a patient with Lennox-Gastaut syndrome

AU - Ishibashi, Hideaki

AU - Morioka, Takato

AU - Shigeto, Hiroshi

AU - Yamamoto, Tomoya

AU - Nishio, Shunji

AU - Fukui, Masashi

PY - 1998/7/1

Y1 - 1998/7/1

N2 - We analyzed the preoperative and postoperative interictal magnetoencephalographic (MEG) patterns in a 32-year-old woman with Lennox- Gastaut syndrome who underwent an anterior corpus callosotomy (CC). A 37- channel biomagnetometer was used for the simultaneous recording of electroencephalogram (EEG) and MEG. Preoperatively, interictal EEG demonstrated a bilaterally synchronous spike and slow wave bursts with a maximum amplitude on the bifrontal region. The waveforms of the MEG were similar but did not completely correspond to those of the EEG. The estimated equivalent current dipoles (ECDs) originating from bilaterally synchronous paroxysmal discharges formed a dense cluster on the bilateral frontal lobes, especially on the deep midfrontal region. After anterior CC, MEG disclosed a marked reduction of the number of ECDs. The preoperative MEG patterns were thought to be representative of interhemispheric synchrony as a large dipole orientation, and these MEG paterns were partly disrupted by anterior CC.

AB - We analyzed the preoperative and postoperative interictal magnetoencephalographic (MEG) patterns in a 32-year-old woman with Lennox- Gastaut syndrome who underwent an anterior corpus callosotomy (CC). A 37- channel biomagnetometer was used for the simultaneous recording of electroencephalogram (EEG) and MEG. Preoperatively, interictal EEG demonstrated a bilaterally synchronous spike and slow wave bursts with a maximum amplitude on the bifrontal region. The waveforms of the MEG were similar but did not completely correspond to those of the EEG. The estimated equivalent current dipoles (ECDs) originating from bilaterally synchronous paroxysmal discharges formed a dense cluster on the bilateral frontal lobes, especially on the deep midfrontal region. After anterior CC, MEG disclosed a marked reduction of the number of ECDs. The preoperative MEG patterns were thought to be representative of interhemispheric synchrony as a large dipole orientation, and these MEG paterns were partly disrupted by anterior CC.

UR - http://www.scopus.com/inward/record.url?scp=0032126331&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032126331&partnerID=8YFLogxK

U2 - 10.1016/S0896-6974(98)00018-8

DO - 10.1016/S0896-6974(98)00018-8

M3 - Article

VL - 11

SP - 202

EP - 207

JO - Epilepsy Research

JF - Epilepsy Research

SN - 0920-1211

IS - 4

ER -