Malignant ovarian tumor composed of endometrioid adenocarcinoma, clear cell adenocarcinoma, squamous cell carcinoma, yolk sac tumor and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation: A case study

Yoshihiro Ohishi, Tsunehisa Kaku, Eisuke Kaneki, Norio Wake, Masazumi Tsuneyoshi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.

Original languageEnglish
Pages (from-to)548-552
Number of pages5
JournalGynecologic Oncology
Volume105
Issue number2
DOIs
Publication statusPublished - May 1 2007

Fingerprint

Clear Cell Adenocarcinoma
Endodermal Sinus Tumor
Endometrioid Carcinoma
Teratoma
Squamous Cell Carcinoma
Germ Cell and Embryonal Neoplasms
Neoplasms
Drug Therapy
Carcinoma

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

Cite this

@article{f0c27a7936e04f5eb1c8928c35796e8a,
title = "Malignant ovarian tumor composed of endometrioid adenocarcinoma, clear cell adenocarcinoma, squamous cell carcinoma, yolk sac tumor and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation: A case study",
abstract = "Background.: Cases of malignant ovarian tumor composed of m{\"u}llerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.",
author = "Yoshihiro Ohishi and Tsunehisa Kaku and Eisuke Kaneki and Norio Wake and Masazumi Tsuneyoshi",
year = "2007",
month = "5",
day = "1",
doi = "10.1016/j.ygyno.2007.02.003",
language = "English",
volume = "105",
pages = "548--552",
journal = "Gynecologic Oncology",
issn = "0090-8258",
publisher = "Academic Press Inc.",
number = "2",

}

TY - JOUR

T1 - Malignant ovarian tumor composed of endometrioid adenocarcinoma, clear cell adenocarcinoma, squamous cell carcinoma, yolk sac tumor and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation

T2 - A case study

AU - Ohishi, Yoshihiro

AU - Kaku, Tsunehisa

AU - Kaneki, Eisuke

AU - Wake, Norio

AU - Tsuneyoshi, Masazumi

PY - 2007/5/1

Y1 - 2007/5/1

N2 - Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.

AB - Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.

UR - http://www.scopus.com/inward/record.url?scp=34247152059&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34247152059&partnerID=8YFLogxK

U2 - 10.1016/j.ygyno.2007.02.003

DO - 10.1016/j.ygyno.2007.02.003

M3 - Article

C2 - 17341430

AN - SCOPUS:34247152059

VL - 105

SP - 548

EP - 552

JO - Gynecologic Oncology

JF - Gynecologic Oncology

SN - 0090-8258

IS - 2

ER -