Malignant ovarian tumor composed of endometrioid adenocarcinoma, clear cell adenocarcinoma, squamous cell carcinoma, yolk sac tumor and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation: A case study

Yoshihiro Ohishi, Tsunehisa Kaku, Eisuke Kaneki, Norio Wake, Masazumi Tsuneyoshi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background.: Cases of malignant ovarian tumor composed of müllerian-type epithelial tumor and malignant germ cell tumor are extremely rare. Case.: We herein report the case of a 34-year-old woman with an ovarian tumor which was composed of endometrioid adenocarcinoma (EAC), clear cell adenocarcinoma (CCC), squamous cell carcinoma, yolk sac tumor (YST) and immature teratoma with prominent neuroectodermal and rhabdomyosarcomatous differentiation. Even after systemic chemotherapy, this intriguing tumor recurred again and again, which is in contrast to pure germ cell tumor which is known to be sensitive to chemotherapy. Conclusion.: No previous cases with an identical composition have been found in the literature. Correct diagnosis of this complex and aggressive tumor is paramount.

Original languageEnglish
Pages (from-to)548-552
Number of pages5
JournalGynecologic Oncology
Volume105
Issue number2
DOIs
Publication statusPublished - May 1 2007

All Science Journal Classification (ASJC) codes

  • Oncology
  • Obstetrics and Gynaecology

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