TY - JOUR
T1 - Malignant syphilis in an HIV-infected patient
AU - Chiba, Takahito
AU - Tashiro, Akari
AU - Moroi, Yoichi
AU - Furue, Masutaka
AU - Taniai, Hiroaki
AU - Furusho, Norihiro
AU - Hayashi, Jun
PY - 2010
Y1 - 2010
N2 - We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.
AB - We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.
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U2 - 10.2336/nishinihonhifu.72.126
DO - 10.2336/nishinihonhifu.72.126
M3 - Article
AN - SCOPUS:84871476718
VL - 72
SP - 126
EP - 128
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 2
ER -