Abstract
We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.
| Original language | English |
|---|---|
| Pages (from-to) | 126-128 |
| Number of pages | 3 |
| Journal | Nishinihon Journal of Dermatology |
| Volume | 72 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Dec 1 2010 |
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All Science Journal Classification (ASJC) codes
- Dermatology
Cite this
Malignant syphilis in an HIV-infected patient. / Chiba, Takahito; Tashiro, Akari; Moroi, Yoichi; Furue, Masutaka; Taniai, Hiroaki; Furusho, Norihiro; Hayashi, Jun.
In: Nishinihon Journal of Dermatology, Vol. 72, No. 2, 01.12.2010, p. 126-128.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Malignant syphilis in an HIV-infected patient
AU - Chiba, Takahito
AU - Tashiro, Akari
AU - Moroi, Yoichi
AU - Furue, Masutaka
AU - Taniai, Hiroaki
AU - Furusho, Norihiro
AU - Hayashi, Jun
PY - 2010/12/1
Y1 - 2010/12/1
N2 - We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.
AB - We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.
UR - http://www.scopus.com/inward/record.url?scp=84871476718&partnerID=8YFLogxK
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U2 - 10.2336/nishinihonhifu.72.126
DO - 10.2336/nishinihonhifu.72.126
M3 - Article
AN - SCOPUS:84871476718
VL - 72
SP - 126
EP - 128
JO - Nishinihon Journal of Dermatology
JF - Nishinihon Journal of Dermatology
SN - 0386-9784
IS - 2
ER -