Malignant syphilis in an HIV-infected patient

Takahito Chiba, Akari Tashiro, Yoichi Moroi, Masutaka Furue, Hiroaki Taniai, Norihiro Furusho, Jun Hayashi

Research output: Contribution to journalArticle

Abstract

We report a case of malignant syphilis in a 32-year-old HIV-infected man who presented with a number of crusted papulonodular skin lesions scattered on his entire body, accompanied by fever and lymphadenitis. The serological test for syphilis, Treponema pallidum latex immunoassay, showed a positive result. A biopsy specimen from the right upper arm was histopathologically compatible with secondary syphilis and immunohistochemically positive for T. pallidum. Based on these serologic, histopathologic and immunohistochemical findings, a definitive diagnosis of malignant syphilis was made, which was successfully treated with oral antibiotics. Malignant syphilis should be considered when ulceronodular skin lesions are encountered in HIV-infected individuals.

Original languageEnglish
Pages (from-to)126-128
Number of pages3
JournalNishinihon Journal of Dermatology
Volume72
Issue number2
DOIs
Publication statusPublished - Dec 1 2010

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Syphilis
HIV
Treponema pallidum
Lymphadenitis
Skin
Latex
Serologic Tests
Immunoassay
Arm
Fever
Anti-Bacterial Agents
Biopsy

All Science Journal Classification (ASJC) codes

  • Dermatology

Cite this

Chiba, T., Tashiro, A., Moroi, Y., Furue, M., Taniai, H., Furusho, N., & Hayashi, J. (2010). Malignant syphilis in an HIV-infected patient. Nishinihon Journal of Dermatology, 72(2), 126-128. https://doi.org/10.2336/nishinihonhifu.72.126

Malignant syphilis in an HIV-infected patient. / Chiba, Takahito; Tashiro, Akari; Moroi, Yoichi; Furue, Masutaka; Taniai, Hiroaki; Furusho, Norihiro; Hayashi, Jun.

In: Nishinihon Journal of Dermatology, Vol. 72, No. 2, 01.12.2010, p. 126-128.

Research output: Contribution to journalArticle

Chiba, T, Tashiro, A, Moroi, Y, Furue, M, Taniai, H, Furusho, N & Hayashi, J 2010, 'Malignant syphilis in an HIV-infected patient', Nishinihon Journal of Dermatology, vol. 72, no. 2, pp. 126-128. https://doi.org/10.2336/nishinihonhifu.72.126
Chiba, Takahito ; Tashiro, Akari ; Moroi, Yoichi ; Furue, Masutaka ; Taniai, Hiroaki ; Furusho, Norihiro ; Hayashi, Jun. / Malignant syphilis in an HIV-infected patient. In: Nishinihon Journal of Dermatology. 2010 ; Vol. 72, No. 2. pp. 126-128.
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