Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer: A pilot study

Muneyuki Masuda, Junichi Fukushima, Hideki Kadota, Kenichi Kamizono, Masayoshi Ejima, Masahiko Taura

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Objective: Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study. Materials and methods: MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle. Results: Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes. Conclusions: Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.

Original languageEnglish
Pages (from-to)392-397
Number of pages6
JournalAuris Nasus Larynx
Volume38
Issue number3
DOIs
Publication statusPublished - Jun 1 2011

Fingerprint

Oropharyngeal Neoplasms
Mandible
Pterygoid Muscles
Lip
Morbidity
Skull Base
Neoplasms
Bone and Bones

All Science Journal Classification (ASJC) codes

  • Surgery
  • Otorhinolaryngology

Cite this

Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer : A pilot study. / Masuda, Muneyuki; Fukushima, Junichi; Kadota, Hideki; Kamizono, Kenichi; Ejima, Masayoshi; Taura, Masahiko.

In: Auris Nasus Larynx, Vol. 38, No. 3, 01.06.2011, p. 392-397.

Research output: Contribution to journalArticle

Masuda, Muneyuki ; Fukushima, Junichi ; Kadota, Hideki ; Kamizono, Kenichi ; Ejima, Masayoshi ; Taura, Masahiko. / Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer : A pilot study. In: Auris Nasus Larynx. 2011 ; Vol. 38, No. 3. pp. 392-397.
@article{a4257a9ced3c4c78b1e3d79905c37abf,
title = "Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer: A pilot study",
abstract = "Objective: Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study. Materials and methods: MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle. Results: Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes. Conclusions: Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.",
author = "Muneyuki Masuda and Junichi Fukushima and Hideki Kadota and Kenichi Kamizono and Masayoshi Ejima and Masahiko Taura",
year = "2011",
month = "6",
day = "1",
doi = "10.1016/j.anl.2010.08.010",
language = "English",
volume = "38",
pages = "392--397",
journal = "Auris Nasus Larynx",
issn = "0385-8146",
publisher = "Elsevier Ireland Ltd",
number = "3",

}

TY - JOUR

T1 - Mandible preserving pull-through oropharyngectomy for advanced oropharyngeal cancer

T2 - A pilot study

AU - Masuda, Muneyuki

AU - Fukushima, Junichi

AU - Kadota, Hideki

AU - Kamizono, Kenichi

AU - Ejima, Masayoshi

AU - Taura, Masahiko

PY - 2011/6/1

Y1 - 2011/6/1

N2 - Objective: Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study. Materials and methods: MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle. Results: Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes. Conclusions: Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.

AB - Objective: Through our experiences in the parapharyngeal space (PPS) surgery, we have learned that it is possible to gain wide exposure of the PPS near to the skull base with a transcervical approach alone. Thus, we presumed that if this type of transcervical approach would be combined with a transoral approach, a less invasive oropharyngectomy without mandibulotomy and lip-splitting might be feasible for the resection of advanced oropharyngeal cancer, sparing the morbidities associated with conventional mandibular swing approach or its modified procedures. We termed this method as a mandible preserving pull-through oropharyngectomy (MPPO) and evaluated its feasibility and efficacy in this pilot study. Materials and methods: MPPO was applied for a series of 7 patients with advanced lateral and/or upper oropharyngeal cancer including 2 patients with T4 stage. Our current application of MPPO excludes tumors, which involves mandibular bone, the higher part of the medial pterygoid muscle, and the lateral pterygoid muscle. Results: Safe and sufficient excision of tumors was feasible by MPPO avoiding morbidities associated with mandibulotomy or lip-splitting without compromising oncological outcomes. Conclusions: Although preliminary, our favorable outcomes indicate that MPPO might be a useful alternative to conventional mandibular swing approach or its modified procedures for selected cases with advanced oropharyngeal cancer. Further accumulation of data is encouraged.

UR - http://www.scopus.com/inward/record.url?scp=79952738828&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79952738828&partnerID=8YFLogxK

U2 - 10.1016/j.anl.2010.08.010

DO - 10.1016/j.anl.2010.08.010

M3 - Article

C2 - 20980111

AN - SCOPUS:79952738828

VL - 38

SP - 392

EP - 397

JO - Auris Nasus Larynx

JF - Auris Nasus Larynx

SN - 0385-8146

IS - 3

ER -