Mania occurring during systemic lupus erythematosus relapse and its amelioration on clinical and neuroimaging follow-up

T. Hirachi, H. Ishii, Y. Tada, T. Noguchi, Y. Haraguchi, H. Tateishi, Y. Mizoguchi, T. A. Kato, T. Kawashima, A. Monji

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Psychiatric manifestations of systemic lupus erythematosus (SLE) that are commonly preceded by organic syndromes include confusional states, anxiety disorder, cognitive dysfunction, mood disorder and psychosis. A 35-year-old woman was admitted to hospital with a relapse of SLE. Laboratory data were exacerbated, with some physical symptoms, and her primary psychiatric symptom was mania. The symptoms were reduced by treatment with prednisolone, methylprednisolone and aripiprazole. Magnetic resonance imaging and single-photon emission computed tomography (SPECT) using 123I-IMP was then performed and analyzed with three-dimensional stereotactic surface projection. This case emphasizes that SLE can commence with organic syndromes and relapse with predominantly psychiatric symptoms, and that the treatment efficacy may be confirmed using a follow-up of SPECT.

Original languageEnglish
Pages (from-to)990-993
Number of pages4
JournalLupus
Volume24
Issue number9
DOIs
Publication statusPublished - Aug 25 2015
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Rheumatology

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