Abstract
Pseudorabies virus (PRV) early protein 0 (EP0) is a transactivator containing the RING finger domain. Analysis of transactivating activity of truncated forms of the EP0 molecule consisting of 410 amino acids revealed that amino-terminal region containing the RING finger domain, amino acids 1 to 84, and the region between amino acids 114 to 242 containing acidic amino acid sequences were required for the transactivation. On the other hand, the mutant consisting of amino acids 1 to 113 exhibited a dominant- negative property.
Original language | English |
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Pages (from-to) | 1001-1009 |
Number of pages | 9 |
Journal | Archives of Virology |
Volume | 141 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jan 1 1996 |
Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Virology