Marked decrease of ribosomal RNA in BmN cells infected with AcMNPV

Ryosuke Fujita, Shinichiro Asano, Ken Sahara, Hisanori Bando

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The baculoviruses Autographa californica multiple nucleopolyhedrovirus (AcMNPV) and Bombyx mori nucleopolyhedrovirus (BmNPV) have highly similar genome sequences but essentially nonoverlapping host ranges. Recent studies demonstrated the arrest of protein synthesis in BmN cells (BmNPV-permissive) infected with AcMNPV. We report here the arrest of cell proliferation in AcMNPV-infected BmN cells involving a marked decrease of ribosomal RNA (rRNA), which was not observed for BmNPV-infected BmN cells or for Sf-9 cells (AcMNPV-permissive) infected with AcMNPV or BmNPV. The arrest of protein synthesis in BmN cells using the de novo protein synthesis inhibitor, cycloheximide, didn't cause the decrease of rRNA, suggesting a unique function of AcMNPV in its ability to decrease rRNA in BmN cells.

Original languageEnglish
Pages (from-to)125-128
Number of pages4
JournalJournal of Insect Biotechnology and Sericology
Volume74
Issue number3
Publication statusPublished - Oct 1 2005
Externally publishedYes

Fingerprint

Autographa californica multiple nucleopolyhedrovirus
Nucleopolyhedrovirus
Bombyx mori nucleopolyhedrovirus
ribosomal RNA
Proteins
Bombyx
Cell proliferation
cells
protein synthesis
Genes
Ribosomal RNA
protein synthesis inhibitors
Baculoviridae
cycloheximide
host range
cell proliferation
Protein Synthesis Inhibitors
Host Specificity
Cycloheximide
genome

All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Applied Microbiology and Biotechnology
  • Business, Management and Accounting(all)
  • Agricultural and Biological Sciences(all)
  • Insect Science
  • Industrial and Manufacturing Engineering

Cite this

Marked decrease of ribosomal RNA in BmN cells infected with AcMNPV. / Fujita, Ryosuke; Asano, Shinichiro; Sahara, Ken; Bando, Hisanori.

In: Journal of Insect Biotechnology and Sericology, Vol. 74, No. 3, 01.10.2005, p. 125-128.

Research output: Contribution to journalArticle

Fujita, Ryosuke ; Asano, Shinichiro ; Sahara, Ken ; Bando, Hisanori. / Marked decrease of ribosomal RNA in BmN cells infected with AcMNPV. In: Journal of Insect Biotechnology and Sericology. 2005 ; Vol. 74, No. 3. pp. 125-128.
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