TY - JOUR
T1 - Mass Fragmentographic Determination of γ‐Aminobutyric Acid and Glutamic Acid in Discrete Amygdaloid Nuclei of Rat Brain
AU - Nakamura, Kaoru
AU - Matsumoto, Takashi
AU - Hirano, Makoto
AU - Kagoshima, Hiroshi
AU - Kuroki, Toshihide
AU - Yao, Hiroshi
AU - Uchimura, Hideyuki
AU - Nakahara, Tatsuo
PY - 1987/6
Y1 - 1987/6
N2 - Abstract: A mass fragmentographic method for the simultaneous quantification of γ‐aminobutyric acid (GABA) and glutamic acid is described. In a convenient one‐step reaction, the two ammo acids were derivatized with pentafluor‐opropionic anhydride and pentafluoropropanol. The deri‐vatization products were stable for several days. The technique has been applied to the assay of GABA and Glu in five amygdaloid nuclei of the rat brain. The GABA level was high in the central and medial nuclei, whereas the Glu level was high in the lateral and basal nuclei. The regional distribution of GABA was different from that of Glu within the amygdaloid nuclei.
AB - Abstract: A mass fragmentographic method for the simultaneous quantification of γ‐aminobutyric acid (GABA) and glutamic acid is described. In a convenient one‐step reaction, the two ammo acids were derivatized with pentafluor‐opropionic anhydride and pentafluoropropanol. The deri‐vatization products were stable for several days. The technique has been applied to the assay of GABA and Glu in five amygdaloid nuclei of the rat brain. The GABA level was high in the central and medial nuclei, whereas the Glu level was high in the lateral and basal nuclei. The regional distribution of GABA was different from that of Glu within the amygdaloid nuclei.
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U2 - 10.1111/j.1471-4159.1987.tb05745.x
DO - 10.1111/j.1471-4159.1987.tb05745.x
M3 - Article
C2 - 2883258
AN - SCOPUS:0023216886
VL - 48
SP - 1842
EP - 1844
JO - Journal of Neurochemistry
JF - Journal of Neurochemistry
SN - 0022-3042
IS - 6
ER -