Massive internal jugular vein tumor thrombus derived from squamous cell carcinoma of the head and neck: two case reports

Takahiro Wakasaki, Hideyuki Kiyohara, Hirofumi Omori, Kensuke Nishi, Kenichi Taguchi, Fumihide Rikimaru, Satoshi Toh, Yuichiro Higaki, Muneyuki Masuda

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Purpose: Tumor thrombosis of the internal jugular vein (IJV) is an extremely rare disease, and the reported cases have been exclusively associated with differentiated thyroid cancer. In the present study, we describe two cases of IJV tumor thrombosis originated from squamous cell carcinoma (SCC), which is the first case report. Methods: Case 1 was a 67-year-old man diagnosed with advanced supraglottic SCC with a massive tumor thrombus in the IJV. He was treated with bio-radiotherapy followed by radical surgery. Case 2 was a 65-year-old woman who underwent radical surgery for SCC of thyroid with tumor thrombosis in the IJV. Results: These cases rapidly developed local recurrences and distant metastases and died within 10 months after surgery. Conclusions: IJV tumor thrombosis originated from SCC apparently reflects extremely aggressive state of the tumor. Recognition and precaution to this condition is essential for the development of a clinically effective treatment strategy.

Original languageEnglish
Pages (from-to)69-74
Number of pages6
JournalOral and Maxillofacial Surgery
Volume21
Issue number1
DOIs
Publication statusPublished - Mar 1 2017

Fingerprint

Jugular Veins
Thrombosis
Squamous Cell Carcinoma
Neoplasms
Rare Diseases
Thyroid Neoplasms
Carcinoma, squamous cell of head and neck
Thyroid Gland
Radiotherapy
Neoplasm Metastasis
Recurrence

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

Cite this

Massive internal jugular vein tumor thrombus derived from squamous cell carcinoma of the head and neck : two case reports. / Wakasaki, Takahiro; Kiyohara, Hideyuki; Omori, Hirofumi; Nishi, Kensuke; Taguchi, Kenichi; Rikimaru, Fumihide; Toh, Satoshi; Higaki, Yuichiro; Masuda, Muneyuki.

In: Oral and Maxillofacial Surgery, Vol. 21, No. 1, 01.03.2017, p. 69-74.

Research output: Contribution to journalArticle

Wakasaki, Takahiro ; Kiyohara, Hideyuki ; Omori, Hirofumi ; Nishi, Kensuke ; Taguchi, Kenichi ; Rikimaru, Fumihide ; Toh, Satoshi ; Higaki, Yuichiro ; Masuda, Muneyuki. / Massive internal jugular vein tumor thrombus derived from squamous cell carcinoma of the head and neck : two case reports. In: Oral and Maxillofacial Surgery. 2017 ; Vol. 21, No. 1. pp. 69-74.
@article{f6a6d2a7b5474c62a56f6ba890d10e65,
title = "Massive internal jugular vein tumor thrombus derived from squamous cell carcinoma of the head and neck: two case reports",
abstract = "Purpose: Tumor thrombosis of the internal jugular vein (IJV) is an extremely rare disease, and the reported cases have been exclusively associated with differentiated thyroid cancer. In the present study, we describe two cases of IJV tumor thrombosis originated from squamous cell carcinoma (SCC), which is the first case report. Methods: Case 1 was a 67-year-old man diagnosed with advanced supraglottic SCC with a massive tumor thrombus in the IJV. He was treated with bio-radiotherapy followed by radical surgery. Case 2 was a 65-year-old woman who underwent radical surgery for SCC of thyroid with tumor thrombosis in the IJV. Results: These cases rapidly developed local recurrences and distant metastases and died within 10 months after surgery. Conclusions: IJV tumor thrombosis originated from SCC apparently reflects extremely aggressive state of the tumor. Recognition and precaution to this condition is essential for the development of a clinically effective treatment strategy.",
author = "Takahiro Wakasaki and Hideyuki Kiyohara and Hirofumi Omori and Kensuke Nishi and Kenichi Taguchi and Fumihide Rikimaru and Satoshi Toh and Yuichiro Higaki and Muneyuki Masuda",
year = "2017",
month = "3",
day = "1",
doi = "10.1007/s10006-016-0600-3",
language = "English",
volume = "21",
pages = "69--74",
journal = "Oral and Maxillofacial Surgery",
issn = "1865-1550",
publisher = "Springer Verlag",
number = "1",

}

TY - JOUR

T1 - Massive internal jugular vein tumor thrombus derived from squamous cell carcinoma of the head and neck

T2 - two case reports

AU - Wakasaki, Takahiro

AU - Kiyohara, Hideyuki

AU - Omori, Hirofumi

AU - Nishi, Kensuke

AU - Taguchi, Kenichi

AU - Rikimaru, Fumihide

AU - Toh, Satoshi

AU - Higaki, Yuichiro

AU - Masuda, Muneyuki

PY - 2017/3/1

Y1 - 2017/3/1

N2 - Purpose: Tumor thrombosis of the internal jugular vein (IJV) is an extremely rare disease, and the reported cases have been exclusively associated with differentiated thyroid cancer. In the present study, we describe two cases of IJV tumor thrombosis originated from squamous cell carcinoma (SCC), which is the first case report. Methods: Case 1 was a 67-year-old man diagnosed with advanced supraglottic SCC with a massive tumor thrombus in the IJV. He was treated with bio-radiotherapy followed by radical surgery. Case 2 was a 65-year-old woman who underwent radical surgery for SCC of thyroid with tumor thrombosis in the IJV. Results: These cases rapidly developed local recurrences and distant metastases and died within 10 months after surgery. Conclusions: IJV tumor thrombosis originated from SCC apparently reflects extremely aggressive state of the tumor. Recognition and precaution to this condition is essential for the development of a clinically effective treatment strategy.

AB - Purpose: Tumor thrombosis of the internal jugular vein (IJV) is an extremely rare disease, and the reported cases have been exclusively associated with differentiated thyroid cancer. In the present study, we describe two cases of IJV tumor thrombosis originated from squamous cell carcinoma (SCC), which is the first case report. Methods: Case 1 was a 67-year-old man diagnosed with advanced supraglottic SCC with a massive tumor thrombus in the IJV. He was treated with bio-radiotherapy followed by radical surgery. Case 2 was a 65-year-old woman who underwent radical surgery for SCC of thyroid with tumor thrombosis in the IJV. Results: These cases rapidly developed local recurrences and distant metastases and died within 10 months after surgery. Conclusions: IJV tumor thrombosis originated from SCC apparently reflects extremely aggressive state of the tumor. Recognition and precaution to this condition is essential for the development of a clinically effective treatment strategy.

UR - http://www.scopus.com/inward/record.url?scp=84996879823&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84996879823&partnerID=8YFLogxK

U2 - 10.1007/s10006-016-0600-3

DO - 10.1007/s10006-016-0600-3

M3 - Article

C2 - 27885568

AN - SCOPUS:84996879823

VL - 21

SP - 69

EP - 74

JO - Oral and Maxillofacial Surgery

JF - Oral and Maxillofacial Surgery

SN - 1865-1550

IS - 1

ER -