Material-driven fibronectin fibrillogenesis

Marco Cantini, Cristina González-García, Virginia Llopis-Hernández, Manuel Salmerón-Sánchez

Research output: Chapter in Book/Report/Conference proceedingConference contribution

9 Citations (Scopus)

Abstract

Material-driven fibronectin fibrillogenesis is a novel route to engineer the network structure and biological activity of fibronectin fibrillar matrices in analogy with their physiological cell-mediated assembly. We identify specific surface chemistries that promote the cell-free formation of physiological-like fibronectin fibrils in a time- and concentration-dependent process. Our most recent and relevant results, reviewed in the chapter, demonstrate the role of this material-induced fibrillogenesis in cell adhesion, extracellular matrix organization and degradation, and cell differentiation.

Original languageEnglish
Title of host publicationProteins at Interfaces III State of the Art
PublisherAmerican Chemical Society
Pages471-496
Number of pages26
ISBN (Print)9780841227965
DOIs
Publication statusPublished - Dec 12 2012
Externally publishedYes

Publication series

NameACS Symposium Series
Volume1120
ISSN (Print)0097-6156
ISSN (Electronic)1947-5918

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'Material-driven fibronectin fibrillogenesis'. Together they form a unique fingerprint.

Cite this