Mathematical treatment of kinetic resolution of chirally labile substrates

M. Kitamura, Makoto Tokunaga, R. Noyori

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Kinetic resolution of chirally unstable compounds prone to racemize has been quantitatively analyzed. Enantiomeric purities of the products as a function of conversion can be graphically displayed. This approach may be useful for designing an efficient asymmetric reaction.

Original languageEnglish
Pages (from-to)1853-1860
Number of pages8
JournalTetrahedron
Volume49
Issue number9
DOIs
Publication statusPublished - Feb 26 1993
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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