Mechanical characterization of floating cell using whole chip deformation mechanism

Keitaro Ito; Shinya Sakuma; Makoto Kaneko; Fumihito Arai

doi:10.1109/MHS.2015.7438299

Mechanical characterization of floating cell using whole chip deformation mechanism

Keitaro Ito, Shinya Sakuma, Makoto Kaneko, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We present a method of cell mechanical characterization using a robot integrated microfluidic chip (robochip). The robochip has a microchannel, a force sensor and an on-chip probe. On-chip probe is actuated by whole chip deformation mechanism. Firstly, we designed the robochip. Secondary, we fabricated the robochip. Finally, we measured the young's modulus of zona pellucida by using Hertz contact theory.

Original language	English
Title of host publication	2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
Publisher	Institute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)	9781479966783
DOIs	https://doi.org/10.1109/MHS.2015.7438299
Publication status	Published - Mar 21 2016
Externally published	Yes
Event	International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 - Nagoya, Japan Duration: Nov 23 2015 → Nov 25 2015

Publication series

Name	2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015

Other

Other	International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015
Country/Territory	Japan
City	Nagoya
Period	11/23/15 → 11/25/15

All Science Journal Classification (ASJC) codes

Biomedical Engineering
Electrical and Electronic Engineering
Biotechnology
Education

Access to Document

10.1109/MHS.2015.7438299

Cite this

Ito, K., Sakuma, S., Kaneko, M., & Arai, F. (2016). Mechanical characterization of floating cell using whole chip deformation mechanism. In 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015 [7438299] (2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/MHS.2015.7438299

Mechanical characterization of floating cell using whole chip deformation mechanism. / Ito, Keitaro; Sakuma, Shinya; Kaneko, Makoto et al.

2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc., 2016. 7438299 (2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Ito, K, Sakuma, S, Kaneko, M & Arai, F 2016, Mechanical characterization of floating cell using whole chip deformation mechanism. in 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015., 7438299, 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015, Institute of Electrical and Electronics Engineers Inc., International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015, Nagoya, Japan, 11/23/15. https://doi.org/10.1109/MHS.2015.7438299

Ito K, Sakuma S, Kaneko M, Arai F. Mechanical characterization of floating cell using whole chip deformation mechanism. In 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc. 2016. 7438299. (2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015). doi: 10.1109/MHS.2015.7438299

Ito, Keitaro ; Sakuma, Shinya ; Kaneko, Makoto et al. / Mechanical characterization of floating cell using whole chip deformation mechanism. 2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015. Institute of Electrical and Electronics Engineers Inc., 2016. (2015 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2015).

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AB - We present a method of cell mechanical characterization using a robot integrated microfluidic chip (robochip). The robochip has a microchannel, a force sensor and an on-chip probe. On-chip probe is actuated by whole chip deformation mechanism. Firstly, we designed the robochip. Secondary, we fabricated the robochip. Finally, we measured the young's modulus of zona pellucida by using Hertz contact theory.

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Mechanical characterization of floating cell using whole chip deformation mechanism

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