Mechanical immobilization of Hela cells on aligned carbon nanotube array

Hiroki Ago, Ei ichiro Uchimura, Takeshi Saito, Satoshi Ohshima, Naoki Ishigami, Masaharu Tsuji, Motoo Yumura, Masato Miyake

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    We demonstrate that an aligned multi-walled carbon nanotube array can immobilize Hela cells through insertion of the nanotube tips into the cell. The cells were immobilized by pressing onto the nanotube array with the aid of mild centrifugal force. The nanotube array fixed a much larger number of cells compared with the flat surface of a Si substrate, indicating strong binding force of the aligned nanotubes toward the cell. This is the first example of mechanical cell immobilization, which offers future applications of the nanotube array for cellular biology, tissue engineering, and biomolecular devices.

    Original languageEnglish
    Pages (from-to)3851-3854
    Number of pages4
    JournalMaterials Letters
    Volume60
    Issue number29-30
    DOIs
    Publication statusPublished - Dec 1 2006

    All Science Journal Classification (ASJC) codes

    • Materials Science(all)
    • Condensed Matter Physics
    • Mechanics of Materials
    • Mechanical Engineering

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  • Cite this

    Ago, H., Uchimura, E. I., Saito, T., Ohshima, S., Ishigami, N., Tsuji, M., Yumura, M., & Miyake, M. (2006). Mechanical immobilization of Hela cells on aligned carbon nanotube array. Materials Letters, 60(29-30), 3851-3854. https://doi.org/10.1016/j.matlet.2006.03.151