TY - JOUR
T1 - Mechanical properties of a giant liposome studied using optical tweezers
AU - Shitamichi, Yoko
AU - Ichikawa, Masatoshi
AU - Kimura, Yasuyuki
N1 - Funding Information:
This work was financially supported by a Grant-in-Aid for Scientific Research from JSPS and by the Priority Area ‘Soft Matter Physics’ from MEXT, Japan. M. Ichikawa was also financially supported by the Sumitomo Foundation and by a Sasakawa Scientific Research Grant from the Japan Science Society.
PY - 2009/9/17
Y1 - 2009/9/17
N2 - The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.
AB - The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.
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U2 - 10.1016/j.cplett.2009.08.018
DO - 10.1016/j.cplett.2009.08.018
M3 - Article
AN - SCOPUS:69949107735
VL - 479
SP - 274
EP - 278
JO - Chemical Physics Letters
JF - Chemical Physics Letters
SN - 0009-2614
IS - 4-6
ER -