Mechanical properties of a giant liposome studied using optical tweezers

Yoko Shitamichi, Masatoshi Ichikawa, Yasuyuki Kimura

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.

Original languageEnglish
Pages (from-to)274-278
Number of pages5
JournalChemical Physics Letters
Volume479
Issue number4-6
DOIs
Publication statusPublished - Sep 17 2009

Fingerprint

Optical tweezers
Liposomes
mechanical properties
Mechanical properties
curves
rigidity
lipids
micrometers
interfacial tension
membranes
Membrane Lipids
Rigidity
Surface tension

All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)
  • Physical and Theoretical Chemistry

Cite this

Mechanical properties of a giant liposome studied using optical tweezers. / Shitamichi, Yoko; Ichikawa, Masatoshi; Kimura, Yasuyuki.

In: Chemical Physics Letters, Vol. 479, No. 4-6, 17.09.2009, p. 274-278.

Research output: Contribution to journalArticle

Shitamichi, Yoko ; Ichikawa, Masatoshi ; Kimura, Yasuyuki. / Mechanical properties of a giant liposome studied using optical tweezers. In: Chemical Physics Letters. 2009 ; Vol. 479, No. 4-6. pp. 274-278.
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