Abstract
The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.
| Original language | English |
|---|---|
| Pages (from-to) | 274-278 |
| Number of pages | 5 |
| Journal | Chemical Physics Letters |
| Volume | 479 |
| Issue number | 4-6 |
| DOIs | |
| Publication status | Published - Sep 17 2009 |
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All Science Journal Classification (ASJC) codes
- Physics and Astronomy(all)
- Physical and Theoretical Chemistry
Cite this
Mechanical properties of a giant liposome studied using optical tweezers. / Shitamichi, Yoko; Ichikawa, Masatoshi; Kimura, Yasuyuki.
In: Chemical Physics Letters, Vol. 479, No. 4-6, 17.09.2009, p. 274-278.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mechanical properties of a giant liposome studied using optical tweezers
AU - Shitamichi, Yoko
AU - Ichikawa, Masatoshi
AU - Kimura, Yasuyuki
PY - 2009/9/17
Y1 - 2009/9/17
N2 - The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.
AB - The mechanical properties of a micrometer-sized giant liposome are studied by deforming it from the inside using dual-beam optical tweezers. As the liposome is extended, its shape changes from a sphere to a lemon shape, and finally, a tubular part is generated. The surface tension σ and the bending rigidity κ of the lipid membrane are obtained from the measured force-extension curve. In a one-phase liposome, it was found that σ increases as the charged component increases but κ remains approximately constant. In a two-phase liposome, the characteristic deformation and the force-extension curve differ from those observed for the one-phase liposome.
UR - http://www.scopus.com/inward/record.url?scp=69949107735&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=69949107735&partnerID=8YFLogxK
U2 - 10.1016/j.cplett.2009.08.018
DO - 10.1016/j.cplett.2009.08.018
M3 - Article
AN - SCOPUS:69949107735
VL - 479
SP - 274
EP - 278
JO - Chemical Physics Letters
JF - Chemical Physics Letters
SN - 0009-2614
IS - 4-6
ER -